AI Article Synopsis

Article Abstract

Epithelial-myoepithelial carcinoma (EMC) is a rare low-grade salivary gland neoplasm. Distant metastasis is rare, and F-fluorodeoxyglucose positron emission tomography/computed tomography (F-FDG PET/CT) has been used to determine the metastatic disease in EMC. Ga-fibroblast activation protein inhibitors (FAPI) PET/CT is a promising imaging modality for diagnostic and theognostic purposes in various malignancies. Comparison studies with F-FDG have investigated the role of Ga-FAPI PET/CT. Herein, we present F-FDG and Ga-FAPI-04 PET/CT findings of a 51-year-old woman with metastatic EMC arising from ex-pleomorphic adenoma of the parotid.

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11589274PMC
http://dx.doi.org/10.4274/mirt.galenos.2023.83435DOI Listing

Publication Analysis

Top Keywords

f-fdg ga-fapi-04
8
ga-fapi-04 pet/ct
8
pet/ct findings
8
epithelial-myoepithelial carcinoma
8
adenoma parotid
8
pet/ct
5
f-fdg
4
findings rare
4
rare epithelial-myoepithelial
4
carcinoma arising
4

Similar Publications

Clinical Explorations of [Ga] Ga-FAPI-04 and [F] FDG Dual-Tracer Total-body PET/CT and PET/MR Imaging.

Semin Nucl Med

November 2024

Department of Nuclear Medicine, Zhongshan Hospital, Fudan University, Shanghai, China; Shanghai Institute of Medical Imaging, Shanghai, China; Institute of Nuclear Medicine, Fudan University, Shanghai, China; Cancer Prevention and Treatment Center, Zhongshan Hospital, Fudan University, Shanghai, China. Electronic address:

Fibroblast activation protein inhibitor (FAPI) and [F]fluorodeoxyglucose ([F]FDG) provide complementary biological information, and FAPI/FDG dual-tracer imaging clinical application is increasing recently. However, optimal protocols for FAPI/FDG dual-tracer positron emission tomography/computed tomography (PET/CT) and PET/magnetic resonance (PET/MR) imaging are still under investigation. Due to its high sensitivity, total-body PET/CT allows for imaging with minimal tracer activity and supports the creation of new dual-tracer PET/CT imaging protocols.

View Article and Find Full Text PDF

We aimed to quantitatively investigate the prognostic value of PET-based biomarkers on [F]FDG and [Ga]Ga-fibroblast activation protein inhibitor (FAPI)-04 PET/CT in patients with highly aggressive neuroendocrine neoplasms (NENs) and to compare the visually assessed differences in uptake on both examinations with progression-free survival (PFS). In this single-center retrospective analysis, 20 patients with high-grade NENs had undergone [F]FDG and [Ga]Ga-FAPI-04 PET. Both PET scans were visually compared, and the presence of [F]FDG-positive, [Ga]Ga-FAPI-04-negative (FDG+/FAPI-) lesions was noted.

View Article and Find Full Text PDF

Neoadjuvant therapy in patients with locally advanced rectal cancer (LARC) has achieved good pathologic complete response (pCR) rates, potentially eliminating the need for surgical intervention. This study investigated preoperative methods for predicting pCR after neoadjuvant short-course radiotherapy (SCRT) combined with immunochemotherapy. Treatment-naïve patients with histologically confirmed LARC were enrolled from February 2023 to July 2023.

View Article and Find Full Text PDF
Article Synopsis
  • - The study investigates the use of Ga-FAPI-04 to assess skeletal muscle injuries, highlighting its effectiveness in analyzing muscle remodeling in various repair scenarios.
  • - Experiments showed that fibroblast activation protein (FAP) levels changed with different injury severities, with Ga-FAPI-04 revealing distinct patterns in muscle uptake and recovery over time.
  • - Overall, Ga-FAPI-04 provided more accurate insights into injury and healing processes compared to traditional imaging methods, emphasizing its potential for clinical applications in skeletal muscle assessment.
View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!