AI Article Synopsis

  • Periprocedural stroke after transcatheter aortic valve implantation (TAVI) is a significant concern, particularly as TAVI is being performed on younger, lower-risk patients.
  • Despite a decade of clinical experience, the rate of stroke during these procedures has remained largely stable, though underreporting is an issue due to various methods of tracking events.
  • This review aims to clarify the current understanding of stroke causes in TAVI patients, assess risk factors, and explore preventive strategies, ultimately guiding better patient risk assessment and the development of future stroke prevention trials.

Article Abstract

Periprocedural stroke after transcatheter aortic valve implantation (TAVI) remains a significant issue, which is associated with high morbidity, and is increasingly important as intervention shifts to younger and lower-risk populations. Over the last decade of clinical experience with TAVI, the incidence of periprocedural stroke has stayed largely unchanged, although it is prone to underreporting due to variation in ascertainment methods. The aetiology of stroke in TAVI patients is multifactorial, and changing risk profiles, differing study populations, and frequent device iterations have made it difficult to discern consistent risk factors. The objective of this review is to analyse and clarify the contemporary published literature on the epidemiology and mechanisms of neurological events in TAVI patients and evaluate potential preventive measures. This summary aims to improve patient risk assessment and refine case selection for cerebral embolic protection devices, while also providing a foundation for designing future trials focused on stroke prevention.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11200663PMC
http://dx.doi.org/10.4244/EIJ-D-23-01087DOI Listing

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