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Astaxanthin (AST), as a natural antioxidant, has broad application prospects in medicine and health products. However, its highly unsaturated structure and significant lipophilic characteristics limit its dispersibility and bioavailability, thereby restricting its application in food, medicines, and nutraceuticals. To overcome these limitations, researchers have proposed the use of nano delivery systems.

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Microfluidic impedance cytometry (MIC) is a label-free technique that characterizes individual flowing particles/cells based on their interaction with a multifrequency electric field. The technique has been successfully applied in different scenarios including life-science research, diagnostics, and environmental monitoring. The aim of this review is to illustrate the fascinating opportunities enabled by the integration of MIC with other microfluidic tools.

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Nanoporous high-entropy alloys and metallic glasses: advanced electrocatalytic materials for electrochemical water splitting.

Chem Commun (Camb)

January 2025

Tianjin Key Laboratory of Advanced Functional Porous Materials, Institute for New Energy Materials and Low-Carbon Technologies, School of Materials Science and Engineering, Tianjin University of Technology, Tianjin 300384, China.

Electrochemical water splitting is a promising approach to convert renewable energy into hydrogen energy and is beneficial for alleviating environmental pollution and energy crises, and is considered a clean method to achieve dual-carbon goals. Electrocatalysts can effectively reduce the reaction energy barrier and improve reaction efficiency. However, designing electrocatalysts with high activity and stability still faces significant challenges, which are closely related to the structure and electronic configuration of catalysts.

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MXenes are a class of 2D transition metal carbides and nitrides (MXT) that have attracted significant interest owing to their remarkable potential in various fields. The unique combination of their excellent electromagnetic, optical, mechanical, and physical properties have extended their applications to the biological realm as well. In particular, their ultra-thin layered structure holds specific promise for diverse biomedical applications.

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Background: Switching between versions of medication products happens commonly despite challenges in achieving bioequivalence and therapeutic equivalence. Central nervous system and psychiatric drugs, especially those that are technically demanding to manufacture and have complex pharmacokinetic properties, such as long-acting injectables (LAIs), pose particular challenges to bioequivalence and safe and efficacious drug switching.

Aims: To assess whether drugs deemed "bioequivalent" are truly interchangeable in drug switching.

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