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| http://dx.doi.org/10.4103/jfmpc.jfmpc_1620_23 | DOI Listing |
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Autoimmune-Like Hepatitis Related to SARS-CoV-2 Vaccination: Towards a Clearer Definition.
Liver Int
January 2025
Epatocentro Ticino, Lugano, Switzerland.
Vaccines are the most effective tool against COVID-19 and are generally safe. Very rare and heterogeneous cases of acute liver injury associated to all types of SARS-CoV-2 vaccines have been reported, mostly with autoimmune features. Epidemiological studies used heterogeneous diagnostic criteria and included different populations.
View Article and Find Full Text PDFCOVID-19 vaccine and the risk of flares in inflammatory arthritis: a systematic literature review and meta-analysis.
Front Immunol
November 2024
Rheumatology Unit, Department of Medicine (DIMED), Padova University Hospital, Padova, Italy.
Introduction: Coronavirus disease 2019 (COVID-19) vaccines aroused concerns about the risk of flares and adverse events in inflammatory arthritis (IA) since the vaccine clinical trials did not specifically investigate this subset of patients.
Methods: A systematic literature review and meta-analysis to summarize the data on joint disease flare and adverse events following immunization (AEFI). Two researchers independently evaluated the literature on Pubmed, Scopus, and EMBASE databases from 22 March 2020 to 30 September 2023.
Healthcare utilization among COVID-19 mRNA vaccine-associated myocarditis cases: a matched retrospective cohort study.
Int J Infect Dis
January 2025
School of Population and Public Health, University of British Columbia, Vancouver, British Columbia, Canada; British Columbia Centre for Disease Control, Vancouver, British Columbia, Canada; University of British Columbia Centre for Disease Control, University of British Columbia, Vancouver, British Columbia, Canada; Centre for Advancing Health Outcomes, St. Paul's Hospital, Vancouver, British Columbia, Canada. Electronic address:
Objectives: We evaluated all-cause healthcare utilization among those with vaccine-associated myocarditis, compared to vaccinees without postvaccination myocarditis.
Methods: We conducted a retrospective cohort study in individuals aged 12 and older who received COVID-19 mRNA vaccination in British Columbia. Exposure was defined as an ED visit or hospitalization for myocarditis within 21 days postvaccination.
Cardiac arrhythmias are commonly noted in patients during infections with and recovery from COVID-19. Arrhythmic manifestations span the spectrum of innocuous and benign to life-threatening and deadly. Various pathophysiological mechanisms have been proposed.
View Article and Find Full Text PDFThe impact of COVID-19 vaccination on patients with congenital heart disease in England: a case-control study.
Heart
November 2024
Division of Cardiovascular Sciences, School of Medical Sciences, Faculty of Biology, Medicine and Health, Manchester Academic Health Science Centre, The University of Manchester, Manchester, UK.
Article Synopsis
- Patients with congenital heart disease (CHD) are at higher risk for severe COVID-19 outcomes, and this study assesses how vaccination impacts their risk levels.* -
- A case-control study compared unvaccinated and vaccinated CHD patients' COVID-19 outcomes, finding that post-vaccination CHD patients had significantly lower hospitalization (0.5% vs 15.8%) and death rates (0.5% vs 4.6%).* -
- Despite the improvements after vaccination, CHD patients remained at an increased risk of hospitalization and death compared to vaccinated controls, with no indication of faster decline in vaccine efficacy or higher rates of complications.*
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