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| http://dx.doi.org/10.3389/ijph.2024.1607460 | DOI Listing |
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The Impact of Vitamin D Supplementation Duration on Early Childhood Developmental Milestones: A Retrospective Study.
Nutrients
December 2024
Unit of Pediatric Clinic, Department of Clinical and Experimental Medicine, University of Catania, 95123 Catania, Italy.
Background: Vitamin D plays a pivotal role in early childhood development, influencing skeletal strength, neuromuscular coordination, and neurodevelopment. This study aimed to evaluate the impact of different durations of Vitamin D supplementation on achieving developmental milestones.
Methods: A retrospective study was conducted on 209 children, divided into two cohorts based on Vitamin D supplementation duration: six months ( = 102) and twelve months ( = 107).
LAP1 Interactome Profiling Provides New Insights into LAP1's Physiological Functions.
Int J Mol Sci
December 2024
Institute of Biomedicine (iBiMED), Department of Medical Sciences, University of Aveiro, 3810-193 Aveiro, Portugal.
The nuclear envelope (NE), a protective membrane bordering the nucleus, is composed of highly specialized proteins that are indispensable for normal cellular activity. Lamina-associated polypeptide 1 (LAP1) is a NE protein whose functions are just beginning to be unveiled. The fact that mutations causing LAP1 deficiency are extremely rare and pathogenic is indicative of its paramount importance to preserving human health, anticipating that LAP1 might have a multifaceted role in the cell.
View Article and Find Full Text PDFA Prospective Study on the Feasibility and Effect of an Optimized Perioperative Care Protocol in Pediatric Neuromuscular Scoliosis Surgery.
J Clin Med
December 2024
Department of Pediatric and Adolescent Medicine, Copenhagen University Hospital, Rigshospitalet, 2100 Copenhagen, Denmark.
: A recent retrospective study conducted by our team identified a high percentage of postoperative pneumonia in children with neuromuscular scoliosis. Based on the findings in that study and our clinical experience, we aimed to assess the effectiveness of an optimized perioperative care protocol. : As part of a prospective study, a multidisciplinary team developed a protocol that included preoperative nutritional and respiratory optimization, intra- and postoperative intravenous glucose infusion, early extubation, and postoperative nutritional optimization.
View Article and Find Full Text PDFConservative Treatment of Neonatal Brachial Plexus Palsy: A Narrative Review.
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Unit of Hand Surgery, Microsurgery and Reconstructive, Department of Orthopaedics and Traumatology, CTO Hospital, 10126 Turin, Italy.
Neonatal brachial plexus palsy (NBPP) is a flaccid paralysis of the upper limbs that occurs in about 0.4 percent of live births. This condition can produce permanent disabilities; to date, there is no consensus on protocols to be applied for the rehabilitation of children with this condition.
View Article and Find Full Text PDFLong-Term Results After Salter Innominate Osteotomy for the Treatment of Developmental Dysplasia of the Hip-Only 8% Rate of Total Hip Arthroplasty at a Median Follow-Up of 22 Years.
Children (Basel)
December 2024
Department of Orthopedics, Radboud University Medical Center, 6525 GA Nijmegen, The Netherlands.
Background/objectives: The redirection or reshaping of the acetabulum might be warranted to attain a concentric and stable hip in children with developmental dysplasia of the hip (DDH). The aim of this study is to assess the late clinical and radiological results, and to determine the number of patients requiring secondary surgery or a total hip arthroplasty at a long-term follow-up.
Methods: Our institution performed 99 Salter osteotomies on 76 patients without underlying neuromuscular conditions over a 21-year period, from 1981 to 2002.
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