AI Article Synopsis
- Measurement of hepatic venous pressure gradient (HVPG) effectively reflects the severity of portal hypertension (PH) and is important for predicting liver disease outcomes, including risk of complications and death.
- HVPG is also key in assessing how well patients respond to treatments like nonselective beta-blockers, supported by evidence from clinical trials.
- Even with available noninvasive tests, HVPG remains crucial in hepatology, so physicians need to understand how to measure, apply, and interpret its results while being aware of possible issues.
Article Abstract
Measurement of hepatic venous pressure gradient (HVPG) effectively mirrors the severity of portal hypertension (PH) and offers valuable insights into prognosis of liver disease, including the risk of decompensation and mortality. Additionally, HVPG offers crucial information about treatment response to nonselective beta-blockers and other medications, with its utility demonstrated in clinical trials in patients with PH. Despite the widespread dissemination and validation of noninvasive tests, HVPG still holds a significant role in hepatology. Physicians treating patients with liver diseases should comprehend the HVPG measurement procedure, its applications, and how to interpret the results and potential pitfalls.
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| http://dx.doi.org/10.1016/j.cld.2024.03.009 | DOI Listing |
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