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Imiquimod 5% cream use in dermatology, side effects and recent patents.
Recent Pat Inflamm Allergy Drug Discov
January 2012
Department of Dermatology, University Sapienza of Rome, Azienda Policlinico Umberto I, Via di Boccea n. 10 int. 16, 00167 Rome, Italy.
Imiquimod is an immune response modifier that stimulates the patient's own immune system to release various chemical substances, such as interferon and interleukin-12. Although, approved by the United States Food and Drug Administration since 1997 as a topical treatment for genital and perianal warts, investigators have found that this product may offer an alternative treatment for a wide variety of medical conditions, such as for actinic keratoses, molluscum contagiosum, genital herpes, and various skin tumours. Clinical trials are now demonstrating the beneficial effects that its administration may have in treating other immune-related, dermatologic disorders.
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