Constipation is common in childhood, and most patients can be successfully managed by their primary care provider. However, some patients will require more specialized management either due to an underlying congenital colorectal disorder such as Hirschsprung disease or anorectal malformation or due to severe functional constipation that is refractory to medical management.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1016/j.yapd.2024.04.001 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Functional gastrointestinal disorders predictors in neonates and toddlers: A machine learning approach to risk assessment.
Heliyon
January 2025
Department of Medical and Surgical Sciences, University of Bologna, Bologna, Italy.
Background: Functional Gastrointestinal Disorders (FGIDs) can pose a great burden on affected children, their families, and the healthcare system. Due to the lack of knowledge about the precise pathophysiology of FGIDs, a proper identification of children at risk to develop FGIDs has never been attempted. The research aims to identify early-life risk factors for FGIDs such as infantile colic, regurgitation, and functional constipation, within the first year of life.
View Article and Find Full Text PDFPresentation and surgical management approaches of giant presacral and sacral schwannomas: a case report and systematic review and meta-analysis.
Eur Spine J
January 2025
Department of Neurosurgery, Faculty of Medicine, Mansoura University, Mansoura, Egypt.
Background: Giant sacral and presacral schwannomas are very rare conditions and their prevalence is estimated to account for only 0.3 to 3.3% of overall schwannomas.
View Article and Find Full Text PDFClinical and laboratory characteristics of solitary rectal ulcer syndrome: a retrospective analysis of 36 case.
Sci Rep
January 2025
Faculty of Medicine, Department of Gastroenterology, Giresun University, Giresun, Turkey.
The primary objective of this study was to evaluate the clinical, laboratory, and histological characteristics of solitary rectal ulcer syndrome (SRUS) and assess the outcomes associated with various management strategies. This retrospective observational study was conducted at Giresun Education and Research Hospital. This study included patients diagnosed with SRUS between January 2020 and January 2024.
View Article and Find Full Text PDFClinical characteristics and surgical outcomes of 72 cases of intestinal and urinary tract deep infiltrating endometriosis.
Am J Transl Res
December 2024
Department of Gastrointestinal Surgery, Suzhou Ninth People's Hospital Suzhou 215200, Jiangsu, China.
The diagnosis and treatment of intestinal and urinary tract deep infiltrating endometriosis (DIE) remain challenging due to its multiple lesions and nonspecific symptoms and signs. This study retrospectively analyzed 72 cases of intestinal and urinary tract DIE, including the clinical characteristics, diagnosis, and treatment outcomes. Among these cases, 11 presented without clinical symptoms, while 61 exhibited obvious clinical symptoms, primarily dysmenorrhea (58.
View Article and Find Full Text PDFPatent review of novel compounds targeting opioid use disorder (2018-2024).
Expert Opin Ther Pat
January 2025
Department of Pharmaceutical and Biomedical Sciences, Rudolph H. Raabe College of Pharmacy, Ohio Northern University, Ada, OH, USA.
Introduction: Opioids have served as a cornerstone in pain management for decades. However, the emergence of increasingly potent synthetic analogs brings forth a range of side effects, including respiratory depression, tolerance, dependence, constipation, and, more importantly, the development of severe and debilitating opioid use disorder (OUD). Search for therapeutics to mitigate OUD has been challenging and this has called for novel approaches that include design of small molecules targeting neuronal circuits involved in addiction (opioid, dopamine, serotonin, norepinephrine, and glutamate receptors, etc.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!