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Clinically Relevant Biomarkers in Connective Tissue Disease-Associated Interstitial Lung Disease. | LitMetric

Clinically Relevant Biomarkers in Connective Tissue Disease-Associated Interstitial Lung Disease.

Rheum Dis Clin North Am

Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine, University of Michigan; Department of Epidemiology, University of Michigan.

Published: August 2024

AI Article Synopsis

  • Interstitial lung disease (ILD) is a serious complication of connective tissue disease (CTD) and significantly impacts patient mortality rates.
  • Timely identification and management of ILD are essential to improve outcomes for patients with CTD.
  • Recent research focuses on both traditional blood tests and advanced -omic biomarkers to better diagnose and predict disease progression in CTD-ILD patients.

Article Abstract

Interstitial lung disease (ILD) complicates connective tissue disease (CTD) with variable incidence and is a leading cause of death in these patients. To improve CTD-ILD outcomes, early recognition and management of ILD is critical. Blood-based and radiologic biomarkers that assist in the diagnosis CTD-ILD have long been studied. Recent studies, including -omic investigations, have also begun to identify biomarkers that may help prognosticate such patients. This review provides an overview of clinically relevant biomarkers in patients with CTD-ILD, highlighting recent advances to assist in the diagnosis and prognostication of CTD-ILD.

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.rdc.2024.03.007DOI Listing

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