Associations of ultraprocessed food consumption with mortality among participants with a history of cancer: a prospective cohort analysis.

Am J Clin Nutr

Department of Epidemiology and Biostatistics, Ministry of Education Key Lab of Environment and Health, School of Public Health, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, P.R. China; Hubei Provincial Clinical Research Center for Colorectal Cancer, Wuhan, Hubei, P.R. China; Wuhan Clinical Research Center for Colorectal Cancer, Wuhan, Hubei, P.R. China. Electronic address:

Published: September 2024

AI Article Synopsis

  • High ultraprocessed food (UPF) consumption has been linked to increased mortality, but its effects on those with a history of cancer were previously unclear.
  • In a study of 13,640 cancer survivors from the UK Biobank, participants’ UPF intake was measured and analyzed for its association with mortality.
  • Results showed that higher UPF consumption correlated with a greater risk of both all-cause and cancer-related mortality, indicating that cancer survivors should be cautious about their UPF intake post-diagnosis.

Article Abstract

Background: Although high ultraprocessed food (UPF) consumption has been linked with increased mortality risk in the general population, whether UPFs harm participants with a history of cancer remains unclear.

Objectives: This study aimed to evaluate the association of UPF consumption with mortality among participants with a history of cancer.

Methods: Prospective cohort analysis was conducted on 13,640 participants with a history of cancer from the UK Biobank. UPFs were defined by the Nova classification. UPF consumption was calculated as the weight proportion of UPFs in the total food consumption. Cox proportional hazard models were used to assess the association between UPF consumption and mortality among participants with a history of cancer.

Results: The median UPF consumption was 29.25% (interquartile range [IQR]: 19.46%-40.62%) for males and 25.81% (IQR: 16.61%-36.35%) for females in the total diet among participants with a history of cancer. During a median follow-up of 10.77 years, 1611 deaths were documented. Multivariable-adjusted hazard ratios (95% confidence intervals) among participants in the highest quartile of UPF consumption relative to the lowest were 1.17 (1.02, 1.35) for all-cause mortality and 1.22 (1.03, 1.44) for cancer-related mortality.

Conclusions: Higher UPF consumption after the diagnosis among participants with a history of cancer is associated with higher risk of mortality.

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.ajcnut.2024.06.010DOI Listing

Publication Analysis

Top Keywords

participants history
28
upf consumption
28
history cancer
20
consumption mortality
12
mortality participants
12
consumption
9
ultraprocessed food
8
food consumption
8
participants
8
prospective cohort
8

Similar Publications

Importance: High-quality colonoscopy reduces the risks of colorectal cancer by increasing the adenoma detection rate. Routine use of an automatic quality control system (AQCS) to assist in colorectal adenoma detection should be considered.

Objective: To evaluate the effect of an AQCS on the adenoma detection rate among colonoscopists who were moderate- and low-level detectors during routine colonoscopy.

View Article and Find Full Text PDF

Importance: Rising prescription medication costs under Medicaid have led to increased procedural prescription denials by health plans. The effect of unresolved denials on chronic condition exacerbation and subsequent acute care utilization remains unclear.

Objective: To examine whether procedural prescription denials are associated with increased net spending through downstream acute care utilization among Medicaid patients not obtaining prescribed medication following a denial.

View Article and Find Full Text PDF

Origin and In-Office Treatment of Retrograde Cricopharyngeus Dysfunction.

JAMA Otolaryngol Head Neck Surg

January 2025

Department of Otolaryngology-Head and Neck Surgery, Foch Hospital, School of Medicine, Paris Saclay University, Paris, France.

Importance: Retrograde cricopharyngeus dysfunction (R-CPD) is an emerging disorder associated with disabling symptoms. The origin of R-CPD remains unknown.

Objective: To investigate the development of symptoms, diagnosis approach, and therapeutic outcomes of R-CPD in patients treated with in-office botulinum toxin injection (BTI) into the cricopharyngeus.

View Article and Find Full Text PDF

Is it possible to return to skiing following long-construct spinal deformity surgery?

Spine Deform

January 2025

Department of Orthopaedic Surgery, Columbia University Irving Medical Center, NewYork-Presbyterian Och Spine Hospital, New York, NY, 10032, USA.

Background: Alpine skiing requires flexibility, endurance, strength and rotational ability, which may be lost after long fusions to the pelvis for adult spinal deformity (ASD). ASD patients may worry about their ability to return to skiing (RTS) postoperatively. There is currently insufficient data for spine surgeons to adequately address questions about when, or if, their patients might RTS.

View Article and Find Full Text PDF

Dengue is the most common arboviral disease globally. It is caused by four distinct but closely related Dengue viruses (DENV-1, -2, -3, and - 4) transmitted through bites of infected Aedes species mosquito vectors. In the last 50 years, incidence has increased 30-fold with increasing geographic expansion to new countries.

View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!