Uncoupling of the endocardial bundles in the left atrium was suggested during modified posterior wall isolation. Although this fact may not be observed because of the possible bridging conduction by epicardial bundles in humans, partially failed transmural ablation in the atrial roof may have iatrogenically unveiled this fact.
Download full-text PDF |
Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11199795 | PMC |
| http://dx.doi.org/10.1002/joa3.13046 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Uncoupling of the endocardial bundles in the left atrium was suggested during modified posterior wall isolation. Although this fact may not be observed because of the possible bridging conduction by epicardial bundles in humans, partially failed transmural ablation in the atrial roof may have iatrogenically unveiled this fact.
View Article and Find Full Text PDFPilot study to evaluate left-to-right ventricular offset in biventricular pacing-comparison of electrocardiographic imaging and ECG.
J Cardiovasc Electrophysiol
June 2024
Department of Biomedical Engineering, Washington University in St. Louis, St. Louis, Missouri, USA.
Introduction: Biventricular pacing (BiVp) improves outcomes in systolic heart failure patients with electrical dyssynchrony. BiVp is delivered from epicardial left ventricular (LV) and endocardial right ventricular (RV) electrodes. Acute electrical activation changes with different LV-RV stimulation offsets can help guide individually optimized BiVp programming.
View Article and Find Full Text PDFMechanism of Blood-Heart-Barrier Leakage: Implications for COVID-19 Induced Cardiovascular Injury.
Int J Mol Sci
December 2021
Department of Physiology, University of Louisville School of Medicine, Louisville, KY 40202, USA.
Article Synopsis
- Blood-heart-barrier (BHB) dysfunction is a key feature of congestive heart failure (CHF) and is particularly relevant in elderly individuals and those affected by COVID-19, although the mechanism behind this is not yet fully understood.
- The research investigates if activation of matrix metalloproteinase-9 (MMP-9) during CHF leads to BHB leakage and aims to see if the drug hydroxychloroquine (HCQ) can inhibit MMP-9, thus preserving the integrity of the endocardial endothelium (EE) and improving heart function.
- Results from a mouse model of CHF showed that MMP-9 activation led to a breakdown in endothelial-myocyte coupling and increased microvascular leakage,
Simulation of diffuse and stringy fibrosis in a bilayer interconnected cable model of the left atrium.
Europace
March 2021
Department of Pharmacology and Physiology, Institute of Biomedical Engineering, Université de Montréal, Montréal, QC H3T 1J4, Canada.
Aims: The aim of this study is to design a computer model of the left atrium for investigating fibre-orientation-dependent microstructure such as stringy fibrosis.
Methods And Results: We developed an approach for automatic construction of bilayer interconnected cable models from left atrial geometry and epi- and endocardial fibre orientation. The model consisted of two layers (epi- and endocardium) of longitudinal and transverse cables intertwined-like fabric threads, with a spatial discretization of 100 µm.
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!