Urticarial Vasculitis.

Immunol Allergy Clin North Am

Department of Dermatology, University of Colorado School of Medicine, Anschutz Medical Campus, 12801 East 17th Avenue, Mail Stop 8127, Aurora, CO 80045, USA. Electronic address:

Published: August 2024

AI Article Synopsis

  • - Urticarial vasculitis is a rare autoimmune disorder marked by long-lasting skin lesions that resemble hives but persist for over 24 hours and are often painful and swollen.
  • - Unlike regular hives, this condition results from inflammation of small blood vessels, causing more severe skin changes and potential bruising.
  • - Diagnosis can be tricky and may need a skin biopsy; treatment focuses on symptom relief with antihistamines and corticosteroids, as well as managing any related autoimmune issues.

Article Abstract

Urticarial vasculitis is a rare autoimmune disorder characterized by persistent edematous papules and plaques on the skin that last longer than 24 hours, often accompanied by systemic symptoms such as joint pain and fever. Unlike common urticaria, this condition involves inflammation of small blood vessels, leading to more severe and long-lasting skin lesions with a tendency to leave a bruiselike appearance. Diagnosis is challenging and may require a skin biopsy. Associated with underlying autoimmune diseases, treatment involves managing symptoms with medications such as antihistamines and corticosteroids, addressing the immune system's dysfunction, and treating any concurrent autoimmune conditions.

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Source
http://dx.doi.org/10.1016/j.iac.2024.03.006DOI Listing

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