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Correction: S100A11 is involved in the progression of colorectal cancer through the desmosome-catenin-TCF signaling pathway.
In Vitro Cell Dev Biol Anim
December 2024
Department of Cell Biology, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, 2-5-1 Shikata-Cho, Kita-Ku, Okayama, 700-8558, Japan.
Interplay between the plasma membrane and cell-cell adhesion maintains epithelial identity for correct polarised cell divisions.
J Cell Sci
March 2024
School of Biological Sciences , University of Southampton, Southampton SO17 1BJ, UK.
Polarised epithelial cell divisions represent a fundamental mechanism for tissue maintenance and morphogenesis. Morphological and mechanical changes in the plasma membrane influence the organisation and crosstalk of microtubules and actin at the cell cortex, thereby regulating the mitotic spindle machinery and chromosome segregation. Yet, the precise mechanisms linking plasma membrane remodelling to cell polarity and cortical cytoskeleton dynamics to ensure accurate execution of mitosis in mammalian epithelial cells remain poorly understood.
View Article and Find Full Text PDFRNA-Sequencing Analysis Identification of Potential Biomarkers for Diagnosis of Sarcopenia.
J Gerontol A Biol Sci Med Sci
October 2023
Medical Genome Center, Research Institute, National Center for Geriatrics and Gerontology, Aichi, Japan.
Sarcopenia is a geriatric disease associated with increased mortality and disability. Early diagnosis and intervention are required to prevent it. This study investigated biomarkers for sarcopenia by using a combination of comprehensive clinical data and messenger RNA-sequencing (RNA-seq) analysis obtained from peripheral blood mononuclear cells.
View Article and Find Full Text PDFAssociation between serum S100A11 levels and glucose metabolism in diabetic process.
Diabetol Metab Syndr
March 2023
Department of Laboratory Medicine, School of Medicine, Chongqing University Three Gorges Hospital, Chongqing University, No.165, Xincheng Avenue, Wanzhou District, Chongqing, 404000, China.
Background: Diabetes mellitus (DM) is a prevalent non-communicable metabolic disease, and S100A11 is a newly identified gene closely related to metabolism. The association of S100A11 with diabetes is unclear. This study aimed to assess the relationship between S100A11 and markers of glucose metabolism in patients with different glucose tolerance and gender.
View Article and Find Full Text PDFRegulated cell death joins in atherosclerotic plaque silent progression.
Sci Rep
February 2022
Department of Proteomics, Institute of Cellular Biology and Pathology "Nicolae Simionescu" of the Romanian Academy, 8, B.P. Hasdeu Street, P.O. Box 35-14, 050568, Bucharest, Romania.
Non-apoptotic regulated cell death (ferroptosis and necroptosis) leads to the release of damage-associated molecular patterns (DAMPs), which initiate and perpetuate a non-infectious inflammatory response. We hypothesize that DAMPs and non-apoptotic regulated cell death are critical players of atherosclerotic plaque progression with inadequate response to lipid-lowering treatment. We aimed to uncover the silent mechanisms that govern the existing residual risk of cardiovascular-related mortality in experimental atherosclerosis.
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