Background: This study aimed to determine predictive clinical and endoscopic ultrasound (EUS) features for pancreatic neuroendocrine tumor (PNET) diagnosis, utilizing EUS-guided tissue acquisition.
Methods: A prospective study from 2018-2022 included patients with pancreatic masses undergoing EUS with elastography. Univariate binomial logistic regression followed by multiple logistic regression with significant predictors was employed. A forward selection algorithm identified optimal models based on predictor numbers. Variables encompassed EUS tumor characteristics (e.g., location, size, margins, echogenicity, vascularity on Doppler, main pancreatic duct dilation, elastography appearance, vascular invasion, and hypoechoic rim), alongside demographic and risk factors (smoking, alcohol, diabetes).
Results: We evaluated 165 patients (24 PNETs). EUS features significantly linked with PNET diagnosis were well-defined margins (79% . 26%, p < 0.001), blue elastography appearance (46% . 9.9%, p < 0.001), vascularization (67% . 25%, p < 0.001), hypoechoic rim (46% . 10%, p < 0.001). The top-performing model, with 89.1% accuracy, included two predictors: a homogeneous lesion (OR, 95% CI) and a hypoechoic rim (OR, 95% CI).
Conclusions: EUS appearance can differentiate PNETs from non-PNETs, with the hypoechoic rim being an independent predictor of PNET diagnosis. The most effective predictive model for PNETs combined the homogeneous lesion and presence of the hypoechoic rim.
Download full-text PDF |
Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11197819 | PMC |
| http://dx.doi.org/10.4183/aeb.2023.407 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
A Veteran Presenting With Fatigue and Weakness.
Fed Pract
October 2024
Veterans Affairs Boston Healthcare System, West Roxbury, Massachusetts.
: A 65-year-old male veteran presented to the Veterans Affairs Boston Healthcare System (VABHS) emergency department with progressive fatigue, dyspnea on exertion, lightheadedness, and falls over the last month. New bilateral lower extremity numbness up to his knees developed in the week prior to admission and prompted him to seek care. Additional history included 2 episodes of transient loss of consciousness resulting in falls and a week of diarrhea, which had resolved.
View Article and Find Full Text PDFAngioleiomyomas of the Extremities and Trunk: An Observational Study.
Acad Radiol
December 2024
Department of Radiology, Mayo Clinic, Rochester, Minnesota, USA. Electronic address:
Article Synopsis
- Angioleiomyomas are benign tumors that develop from the smooth muscle of blood vessels and can occur in various body regions, though they are commonly found in the head, neck, and uterus.
- A study examined 191 patients with trunk or extremity angioleiomyomas, finding that a high percentage experienced pain, with most tumors located in the lower extremities; imaging revealed non-specific soft tissue masses and specific characteristics on ultrasound and cross-sectional imaging.
- Key imaging features to identify angioleiomyomas include a soft tissue mass near blood vessels, hypoechoic nature with internal vascularity on ultrasound, and certain MRI characteristics, which can help differentiate them from other conditions.
Accuracy of ultrasound-guided fine-needle aspiration cytology in evaluation of thyroid nodules using different ultrasonographic and cytological features.
Cytopathology
November 2024
Department of Medical Laboratory, Faculty of Medicine and Health Sciences, University of Science and Technology, Sana'a, Yemen.
Background: Fine-needle aspiration cytology (FNAC) is a reliable method for preoperative evaluation of thyroid nodules particularly if ultrasound-guided (USG-FNAC). The main purpose of this study is to evaluate the efficacy of USG-FNAC and its accuracy.
Methods: We retrospectively studied 212 thyroidectomy cases with preoperative ultrasonography and FNAC data during the period 2015-2022 using TI-RADS for final ultrasound diagnosis and Bethesda system for cytological diagnosis.
A MODEL TO PREDICT DIAGNOSIS OF PANCREATIC NEUROENDOCRINE TUMORS BASED ON EUS IMAGING FEATURES.
Acta Endocrinol (Buchar)
June 2024
Clinical Institute Fundeni - Gastroenterology 258 Fundeni Rd, Bucharest, 022238, Romania.
Background: This study aimed to determine predictive clinical and endoscopic ultrasound (EUS) features for pancreatic neuroendocrine tumor (PNET) diagnosis, utilizing EUS-guided tissue acquisition.
Methods: A prospective study from 2018-2022 included patients with pancreatic masses undergoing EUS with elastography. Univariate binomial logistic regression followed by multiple logistic regression with significant predictors was employed.
Ultrasound and CT findings of subcutaneous metastases in trunk and pelvis: a comprehensive analysis.
Skeletal Radiol
December 2024
Department of Radiology, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea.
Objective: This study aimed to describe the ultrasound, CT findings, and clinical manifestations of pathologically confirmed metastases involving the subcutaneous fat layer of the trunk and pelvis.
Materials And Methods: We included 30 patients with subcutaneous metastases in the trunk and pelvis, verified by ultrasound-guided biopsy. We comprehensively reviewed ultrasound findings of all 30 patients and contrast-enhanced CT findings of 25 patients obtained before biopsy.
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!