A Lindley-binomial model for analyzing the proportions with sparseness and excessive zeros.

J Appl Stat

Department of Mathematics and Statistics, University of Regina, Sask, Canada.

Published: July 2023

Proportional data arise frequently in a wide variety of fields of study. Such data often exhibit extra variation such as over/under dispersion, sparseness and zero inflation. For example, the hepatitis data present both sparseness and zero inflation with 19 contributing non-zero denominators of 5 or less and with 36 having zero seropositive out of 83 annual age groups. The whitefly data consists of 640 observations with 339 zeros (53%), which demonstrates extra zero inflation. The catheter management data involve excessive zeros with over 60% zeros averagely for outcomes of 193 urinary tract infections, 194 outcomes of catheter blockages and 193 outcomes of catheter displacements. However, the existing models cannot always address such features appropriately. In this paper, a new two-parameter probability distribution called Lindley-binomial (LB) distribution is proposed to analyze the proportional data with such features. The probabilistic properties of the distribution such as moment, moment generating function are derived. The Fisher scoring algorithm and EM algorithm are presented for the computation of estimates of parameters in the proposed LB regression model. The issues on goodness of fit for the LB model are discussed. A limited simulation study is also performed to evaluate the performance of derived EM algorithms for the estimation of parameters in the model with/without covariates. The proposed model is illustrated through three aforementioned proportional datasets.

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11198151PMC
http://dx.doi.org/10.1080/02664763.2023.2237212DOI Listing

Publication Analysis

Top Keywords

excessive zeros
8
proportional data
8
sparseness inflation
8
outcomes catheter
8
data
6
lindley-binomial model
4
model analyzing
4
analyzing proportions
4
proportions sparseness
4
sparseness excessive
4

Similar Publications

Empirical networks are sparse: Enhancing multiedge models with zero-inflation.

PNAS Nexus

January 2025

Chair of Systems Design, ETH Zurich, Weinbergstrasse 56/58, Zurich 8092, Switzerland.

Real-world networks are sparse. As we show in this article, even when a large number of interactions is observed, most node pairs remain disconnected. We demonstrate that classical multiedge network models, such as the , configuration models, and stochastic block models, fail to accurately capture this phenomenon.

View Article and Find Full Text PDF

Goal: While studies have examined quality and health outcomes related to the Centers for Medicare & Medicaid Services' (CMS's) Hospital Value-Based Purchasing (HVBP) Program, a significant gap exists in the literature regarding the relationship between pay-for-performance initiatives and hospital financial performance in the program's Efficiency and Cost Reduction domain. This study examined the association between hospitals' cost inefficiency and participation in the HVBP Program by estimating the probability and magnitude of improvement or achievement in the program's Efficiency and Cost Reduction domain.

Methods: The 2014-2019 Efficiency and Cost Reduction domain data were obtained from CMS and merged with the American Hospital Association's Annual Survey Database.

View Article and Find Full Text PDF

The class of a-b power interaction models, proposed by Yu et al. (2024), provides a general framework for modeling sparse compositional count data with pairwise feature interactions. This class includes many distributions as special cases and enables zero count handling through power transformations, making it especially suitable for modern high- throughput sequencing data with excess zeros, including single-cell RNA-Seq and amplicon sequencing data.

View Article and Find Full Text PDF

Background: Carbapenem-resistant (CRE) are an urgent threat to healthcare, but the epidemiology of these antimicrobial-resistant organisms may be evolving in some settings since the COVID-19 pandemic. An updated analysis of hospital-acquired CRE (HA-CRE) incidence in community hospitals is needed.

Methods: We retrospectively analyzed data on HA-CRE cases and antimicrobial utilization (AU) from two community hospital networks, the Duke Infection Control Outreach Network (DICON) and the Duke Antimicrobial Stewardship Outreach Network (DASON) from January 2013 to June 2023.

View Article and Find Full Text PDF

ADAPT: Analysis of Microbiome Differential Abundance by Pooling Tobit Models.

Bioinformatics

November 2024

Department of Biostatistics, University of Michigan, 1415 Washington Heights, Ann Arbor, Michigan, 48109, United States.

Motivation: Microbiome differential abundance analysis (DAA) remains a challenging problem despite multiple methods proposed in the literature. The excessive zeros and compositionality of metagenomics data are two main challenges for DAA.

Results: We propose a novel method called "Analysis of Microbiome Differential Abundance by Pooling Tobit Models" (ADAPT) to overcome these two challenges.

View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!