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Melanoma, primarily caused by solar ultraviolet (UV) radiation, can be prevented by the use of sunscreens. However, the use of synthetic sunscreens raises environmental concerns. Natural compounds with antioxidant photoprotective properties and cytotoxic effects against cancer cells can be promising for the prevention and treatment of melanoma with less environmental effect. This study focuses on essential oil (EO) for photoprotection and antitumor applications. EO was hydrodistilled from leaves with a 0.59% yield. Gas chromatography-mass spectrometry detected monoterpenes and sesquiterpenes. Nanoemulsions were prepared with (NE-EO) and without EO (NE-B) using the phase inversion method, showing good stability, spherical or oval morphology, and a pseudoplastic profile. Photoprotective activity assessed spectrophotometrically showed that the NE-EO was more effective than NE-B and free EO. Antioxidant activity evaluated by DPPH and ABTS methods indicated that pure and nanoemulsified EO mainly inhibited the ABTS radical, showing IC 40.72 and 5.30 µg/mL, respectively. Cytotoxicity tests on L-929 mouse fibroblasts, NGM human melanocyte, B16-F10 melanoma, and MeWo human melanoma revealed that EO and NE-EO were more cytotoxic to melanoma cells than to non-tumor cells. The stable NE-EO demonstrates potential for melanoma prevention and treatment. Further research is required to gain a better understanding of these activities.
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http://dx.doi.org/10.3390/ph17060721 | DOI Listing |
Front Vet Sci
December 2024
Hunan Provincial Key Laboratory of the Traditional Chinese Medicine Agricultural Biogenomics, Changsha Medical University, Changsha, Hunan, China.
, a perennial herb belonging to the Zingiberaceae family, has a long history of traditional medicinal use. The present study evaluated the efficacy of different concentrations of essential oil (AEO) on the growth performance, serum antioxidation capacities, immune function, apparent digestibility of nutrients, and gut microbiota in fattening pigs. A total of 120 pigs were divided into five treatments, with six replicates each and four pigs per replicate.
View Article and Find Full Text PDFHeliyon
December 2024
Department of Food Science and Engineering, Faculty of Agriculture, University of Zanjan, Zanjan, 45371-38791, Iran.
The current research focused on examining the effect of a coating made from Balangu seed mucilage (TSM-BM) and gelatin (Ge), with varying concentrations of dill essential oil (DEO) (0 %, 1 %, and 2 %) and zinc oxide nanoparticles (ZnO-np) (0 % and 0.5 %), on the quality characteristics of cherries stored at 4 °C over intervals of 0, 4, 7, 11, 18, and 25 days. The study noted that the application of this coating, particularly when combined with DEO and ZnO-np, significantly reduced the rate of changes in several parameters, including weight loss, firmness, titratable acidity, pH, total soluble solids, ascorbic acid, total anthocyanin content, total phenolic content, and antioxidant activity (p˂0.
View Article and Find Full Text PDFHeliyon
December 2024
Department of Food Science, Czech University of Life Sciences Prague, Kamycka 129, Prague 6, Czech Republic.
The growing demand for alternative plant protection products (PPP) that are more environmentally friendly leads to the investigation of novel approaches in agriculture. The use of plant extracts as PPP belongs to one of the most intensively investigated areas. This study aimed to evaluate if the partial substitution of conventional pesticides with selected botanicals (seaweed extract, orange essential oil, thyme essential oil, and a hop extract) will have the same protective effect against ans as conventional potato treatment.
View Article and Find Full Text PDFJ Biomed Mater Res A
January 2025
Institute for Fiber Engineering and Science (IFES), Interdisciplinary Cluster for Cutting Edge Research (ICCER), Shinshu University, Ueda, Japan.
This study aimed to develop polyvinyl alcohol (PVA) and kappa-carrageenan (κCA) biocomposite films using a Pickering emulsion technique for wound care applications. Juniper essential oil and modified sepiolite were incorporated to enhance functionality, with films prepared via solvent casting and characterized for structural, thermal, and mechanical properties. The PCOS-2 film exhibited the highest mechanical performance, with Young's modulus of 6.
View Article and Find Full Text PDFFood Chem
December 2024
Department of Chemistry, North Eastern Regional Institute of Science and Technology, Nirjuli, Itanagar, Arunachal Pradesh 791109, India. Electronic address:
Coriander (Coriandrum sativum L.) is a nutraceutically renowned annual herb from Apiaceae family and used in cuisines in different countries in different ways to enhance the tastes, flavour and nutritional values of foods. Fruit (seed) has several medicinally valuable chemical components viz.
View Article and Find Full Text PDFEnter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!