AI Article Synopsis
- * Afzelin, a flavonoid found in various plants, shows significant biological benefits and may help address diseases related to oxidative stress and abnormal cell death mechanisms.
- * The review discusses afzelin's potential in treating neurodegenerative diseases and cancer by reducing oxidative stress, managing inflammation, and supporting cellular regeneration.
Article Abstract
Neurodegenerative diseases (Alzheimer's disease, Parkinson's disease, Huntington's disease, and others) and cancer, seemingly disparate in their etiology and manifestation, exhibit intriguing associations in certain cellular and molecular processes. Both cancer and neurodegenerative diseases involve the deregulation of cellular processes such as apoptosis, proliferation, and DNA repair and pose a significant global health challenge. Afzelin (kaempferol 3-O-rhamnoside) is a flavonoid compound abundant in various plant sources. Afzelin exhibits a diverse range of biological activities, offering promising prospects for the treatment of diseases hallmarked by oxidative stress and deregulation of cell death pathways. Its protective potential against oxidative stress is also promising for alleviating the side effects of chemotherapy. This review explores the potential therapeutic implications of afzelin, including its capacity to mitigate oxidative stress, modulate inflammation, and promote cellular regeneration in neurodegenerative and cancer diseases.
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Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11206995 | PMC |
| http://dx.doi.org/10.3390/ph17060701 | DOI Listing |
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