AI Article Synopsis
- - Chronic wounds are a significant healthcare challenge globally, especially impacting the quality of life for the elderly in developed countries.
- - Current research is exploring the repurposing of existing cardiovascular medications, like sartans, beta-blockers, and statins, for new uses in wound treatment.
- - This review aims to analyze how these cardiovascular agents work at a molecular level in promoting wound healing and their potential benefits in chronic wound care.
Article Abstract
Chronic wound treatments pose a challenge for healthcare worldwide, particularly for the people in developed countries. Chronic wounds significantly impair quality of life, especially among the elderly. Current research is devoted to novel approaches to wound care by repositioning cardiovascular agents for topical wound treatment. The emerging field of medicinal products' repurposing, which involves redirecting existing pharmaceuticals to new therapeutic uses, is a promising strategy. Recent studies suggest that medicinal products such as sartans, beta-blockers, and statins have unexplored potential, exhibiting multifaceted pharmacological properties that extend beyond their primary indications. The purpose of this review is to analyze the current state of knowledge on the repositioning of cardiovascular agents' use and their molecular mechanisms in the context of wound healing.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11206936 | PMC |
| http://dx.doi.org/10.3390/molecules29122938 | DOI Listing |
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