Natural astaxanthin is in high demand due to its multiple health benefits. The microalga has been used for the commercial production of astaxanthin. In this study, we investigated the effects of six different media with and without a nitrogen source and supplementation with nine organic compounds on the growth and astaxanthin accumulation of . The highest astaxanthin contents were observed in cultures of in Jaworski's medium (JM), with a level of 9.099 mg/L in JM with a nitrogen source supplemented with leucine (0.65 g/L) and of 20.484 mg/L in JM without a nitrogen source supplemented with sodium glutamate (0.325 g/L). Six of the nine organic compounds examined (leucine, lysine, alanine, sodium glutamate, glutamine, and cellulose) enhanced the production of astaxanthin in , while malic acid, benzoic acid, and maltose showed no beneficial effects.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11205594PMC
http://dx.doi.org/10.3390/microorganisms12061040DOI Listing

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