According to current guidelines, only clinical surveillance is recommended for patients with moderate aortic valve stenosis (AS), while aortic valve replacement may be considered in patients undergoing surgery for other indications. Recent studies have shown that moderate AS is associated with a high risk of adverse cardiovascular events, including death, especially in patients with left ventricular dysfunction. In this context, multimodality imaging can help to improve the accuracy of moderate AS diagnosis and to assess left ventricular remodeling response. This review discusses the natural history of this valve disease and the role of multimodality imaging in the diagnostic process, summarizes current evidence on the medical and non-medical management, and highlights ongoing trials on valve replacement.
Download full-text PDF |
Source |
---|---|
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11204855 | PMC |
http://dx.doi.org/10.3390/jcm13123478 | DOI Listing |
J Bone Miner Res
January 2025
Departments of Medicine and Radiology, University of Manitoba, Winnipeg, Canada.
Vertebral fracture assessment (VFA) images from bone density machines enable the automated machine learning assessment of abdominal aortic calcification (ML-AAC), a marker of cardiovascular disease (CVD) risk. The objective of this study was to describe the risk of a major adverse cardiovascular event (MACE, from linked health records) in patients attending routine bone mineral density (BMD) testing and meeting specific criteria based on age, BMD, height loss, or glucocorticoid use have a VFA in the Manitoba Bone Mineral Density Registry. The cohort included 10 250 individuals (mean 75.
View Article and Find Full Text PDFEur Heart J Imaging Methods Pract
July 2024
Department of Circulation and Medical Imaging, Faculty of Medicine and Health Science, Norwegian University of Science and Technology (NTNU), Prinsesse Kristinas gate 3, Trondheim 7030, Norway.
Aims: To improve quantification of valvular regurgitation, a 3D high-pulse repetition frequency Doppler (3D HPRFD) method was developed for regurgitant volume (RVol) estimation from transthoracic echocardiography (TTE). Although successfully applied and in selected clinical cases, a systematic clinical validation of 3D HPRFD has not been published. Hence, our aims were to investigate (i) feasibility of 3D HPRFD and (ii) correlation between 3D HPRFD and RVol estimates obtained by the 2D proximal isovelocity surface area (PISA) method and cardiac magnetic resonance (CMR) in patients with either aortic regurgitation (AR) or mitral regurgitation (MR).
View Article and Find Full Text PDFCureus
December 2024
Medical Strategic Affairs, Torrent Pharmaceuticals Ltd., Ahmedabad, IND.
Introduction: Elevated central aortic pressure, cardiac output and peripheral vascular resistance contribute to high morbidity in relation to end organ dysfunction in obstructive and non-obstructive coronary artery disease (NOCAD) cases despite revascularization. Bisoprolol preempts further progression of left ventricular dysfunction in such cases due to anti-ischemic and anti-hypertensive effects, further extending its evaluation in local Indian settings.
Methods: Post-hoc analyses of NOCAD patients with epicardial stenosis (N=378, 30 to 70% stenosis) from cross-sectional analyses conducted across eighty centers in India.
Radiol Cardiothorac Imaging
February 2025
From the Department of Cardiology, Houston Methodist DeBakey Heart & Vascular Center, 6550 Fannin St, Smith Tower, Ste 1801, Houston, TX 77030 (M.M., P.B., V.C., M.S., M.R., S.F.N., W.A.Z., D.J.S.); and Department of Pathology and Genomic Medicine, Houston Methodist Hospital Research Institute, Houston, Tex (D.T.N., E.A.G.).
Purpose To investigate the determinants and effect of right ventricular (RV) dysfunction in aortic regurgitation (AR) using cardiac MRI. Materials and Methods This study included patients with moderate or severe AR who were enrolled in the DEBAKEY-CMR registry between January 2009 and June 2020. Patients with previous valve intervention, cardiomyopathy deemed unrelated to AR, severe aortic stenosis, and other confounders were excluded.
View Article and Find Full Text PDFInt J Cardiovasc Imaging
December 2024
Cardiology, Hospital Universitario Marqués de Valdecilla, IDIVAL, University of Cantabria, Santander, Spain.
Hand-held ultrasound devices (HHUD) are increasingly used in routine clinical practice, though they lacked continuous (CW) Doppler capability until recent times. There is limited evidence on the utility of HHUD in assessing aortic stenosis (AS) in real-world settings. Our goal was to validate a new HHUD with CW Doppler assessing AS hemodynamic severity.
View Article and Find Full Text PDFEnter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!