AI Article Synopsis
- * A study conducted at a pediatric clinic analyzed data from children hospitalized for iGAS infections in 2023, revealing clinical patterns and groundbreaking insights into the infections.
- * Between 2016 and 2023, the number of GAS infections remained relatively stable, but 2023 saw a significant increase in pediatric cases, with common symptoms including high fever, tachycardia, and vomiting; specific lab results were also noted.
Article Abstract
Since October 2022, alerts have spread from several countries about the increase in invasive group A streptococcal (iGAS) and scarlet fever cases affecting young children. We aim to analyze the epidemiology of GAS infections in the last 12 years in our hospital and identify the clinical features of invasive cases observed in 2023. We conducted a retrospective study enrolling children and adolescents hospitalized at our pediatric clinic from January to December 2023 for a definitive diagnosis of iGAS infection. Clinical, laboratory, and imaging data were collected and analyzed. Comparing 2016 and 2023, we observed a similar number of GAS infections (65 vs. 60 cases). Five children with iGAS infection were hospitalized between March and April 2023. The median age was five years. At admission, all patients showed tachycardia disproportionate to their body temperature. Vomiting was a recurrent symptom (80%). Laboratory tests mostly showed lymphopenia, hyponatremia, and high inflammatory markers. The number of pediatric iGAS cases significantly increased in 2023. Clinical (pre-school-aged children with high fever, unexplained tachycardia, and vomiting) and laboratory parameters (high procalcitonin levels, hyponatremia, and lymphopenia) could help identify and suspect a potential iGAS infection.
Download full-text PDF |
Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11201606 | PMC |
| http://dx.doi.org/10.3390/children11060614 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Invasive group A streptococcal infections as a consequence of coexisting or previous viral infection in the post-COVID-19 pandemic period.
J Infect Public Health
December 2024
Department of Infectious Diseases and Child Neurology, Institute of Paediatrics, Poznan University of Medical Sciences, Poland.
Background: Group A Streptococci (GAS) may cause infections of the pharynx and soft tissues and invasive infections in children (iGAS). A significant increase in severe iGAS infections has been reported in Europe since the fall of 2022.
Objectives: This retrospective study aims to analyse clinical data of children with invasive and non-invasive GAS infections in the post-COVID-19 pandemic era, searching for predisposing factors to developing invasive infections.
Trends in the growing impact of group A Streptococcus infection on public health after COVID-19 pandemic: a multicentral observational study in Okayama, Japan.
Eur J Clin Microbiol Infect Dis
December 2024
Department of Infectious Diseases, Okayama University Hospital, 2-5-1 Shikata-cho, Okayama, Okayama, 700-8558, Japan.
Purpose: Following the COVID-19 pandemic, group A Streptococcus (GAS) infection has been surging worldwide. We aimed to compare the disease burden between notified cases of streptococcal toxic shock syndrome (STSS) and unreported GAS infections.
Methods: This is a multicentral observational study, retrospectively performed at seven hospitals in Okayama prefecture in Japan from January 2022, to June 2024.
Emergence of T4SS-type-ICE-carrying emm28 Streptococcus pyogenes causing invasive infection in Shanghai, China.
J Glob Antimicrob Resist
December 2024
Research and Translational Laboratory of Acute Injury and Secondary Infection, Minhang Hospital, Fudan University, Shanghai, China.; Department of Laboratory Medicine, Minhang Hospital, Fudan University, Shanghai, China.. Electronic address:
Objectives: Invasive group A streptococcal (iGAS) infections have been rising in Europe, Australia, and the USA, but few data from China are available. This study was intended to provide local data to mirror the characteristics of iGAS infections in China.
Methods: Retrospective analysis was performed on the clinical data of the iGAS infections during 2014-2023 in a tertiary hospital in Shanghai, China.
Primary Bacterial Peritonitis in a Young Man: A Rare Manifestation of Invasive Group A Streptococcal Infection.
Cureus
November 2024
Intensive Care Unit, Centre Hospitalier de Wallonie Picarde, Tournai, BEL.
Group A (GAS) is a ubiquitous pathogen responsible for a wide range of infections, from superficial to severe invasive forms (iGAS). Among these, primary bacterial peritonitis (PBP) due to GAS is a rare but severe presentation. Recent epidemiological data indicate a significant rise in iGAS cases globally, which may be linked to changes in post-pandemic pathogen circulation.
View Article and Find Full Text PDFGenomic epidemiology of invasive Group A Streptococcus infections in Argentina, 2023: high prevalence of 1-global and detection of 1 hypervirulent lineages.
Microbiol Spectr
November 2024
Servicio Bacteriología Especial, Instituto Nacional de Enfermedades Infecciosas, Ciudad Autónoma de Buenos Aires, Buenos Aires, Argentina.
Article Synopsis
- * A dominant prevalence of the 1-type strain was found, with the identification of two harmful international variants (1-UK and 1-DK) and a local variant (1-ST1319).
- * The findings highlight the need for ongoing genomic surveillance to address the rise of invasive infections and monitor the spread of virulent strains across South America.
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!