AI Article Synopsis
- Microbes are the most abundant life forms on Earth, but their diversity is often overlooked, particularly in vertebrate models where studying host-microbiome interactions is complex.
- In a natural setting, animal guts have a variety of microbial species, but lab studies typically focus on just one, limiting our understanding.
- The review discusses how microbial metabolites, drugs, and host genetics interact, using specific examples to highlight ongoing research in host-microbe-metabolite relationships.
Article Abstract
Microbes constitute the most prevalent life form on Earth, yet their remarkable diversity remains mostly unrecognized. Microbial diversity in vertebrate models presents a significant challenge for investigating host-microbiome interactions. The model organism has many advantages for delineating the effects of host genetics on microbial composition. In the wild, the gut contains various microbial species, while in the laboratory it is usually a host for a single bacterial species. There is a potential host-microbe interaction between microbial metabolites, drugs, and phenotypes. This mini-review aims to summarize the current understanding regarding the microbiome in . Examples using to study host-microbe-metabolite interactions are discussed.
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Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11203780 | PMC |
| http://dx.doi.org/10.3390/ijms25126670 | DOI Listing |
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