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Venous gas emboli (VGE) in 2-D echocardiographic images following movement: grading and association with cumulative incidence of decompression sickness.
Diving Hyperb Med
March 2025
Navy Experimental Diving Unit, Panama City, Florida, USA.
Introduction: Venous gas emboli (VGE) are a common surrogate experimental endpoint for decompression sickness (DCS). VGE numbers are graded, and the peak post-dive grade is associated with the probability of DCS (PDCS). VGE are typically graded with the subject at rest when bubble numbers are stable, and again after limb flexions which elicit a transient shower of bubbles.
View Article and Find Full Text PDFEuropean Consensus on Malabsorption-UEG & SIGE, LGA, SPG, SRGH, CGS, ESPCG, EAGEN, ESPEN, and ESPGHAN: Part 2: Screening, Special Populations, Nutritional Goals, Supportive Care, Primary Care Perspective.
United European Gastroenterol J
March 2025
Department of Internal Medicine and Medical Therapeutics, University of Pavia, Pavia, Italy.
Malabsorption is a complex and multifaceted condition characterised by the defective passage of nutrients into the blood and lymphatic streams. Several congenital or acquired disorders may cause either selective or global malabsorption in both children and adults, such as cystic fibrosis, exocrine pancreatic insufficiency (EPI), coeliac disease (CD) and other enteropathies, lactase deficiency, small intestinal bacterial overgrowth (SIBO), autoimmune atrophic gastritis, Crohn's disease, and gastric or small bowel resections. Early recognition of malabsorption is key for tailoring a proper diagnostic work-up for identifying the cause of malabsorption.
View Article and Find Full Text PDFMutational constraint analysis workflow for overlapping short open reading frames and genomic neighbors.
BMC Genomics
March 2025
Institute for Human Genetics and Genomic Medicine Medical Faculty, RWTH Aachen University Hospital, Pauwelsstrasse 30, D-52074, Aachen, North-Rhine-Westphalia, Germany.
Understanding the dark genome is a priority task following the complete sequencing of the human genome. Short open reading frames (sORFs) are a group of largely unexplored elements of the dark genome with the potential for being translated into microproteins. The definitive number of coding and regulatory sORFs is not known, however they could account for up to 1-2% of the human genome.
View Article and Find Full Text PDFChild public health indicators for fragile, conflict-affected, and vulnerable settings: A scoping review.
PLOS Glob Public Health
March 2025
Faculty of Infectious Tropical Diseases, London School of Hygiene and Tropical Medicine, London, United Kingdom.
Children and young people are disproportionately vulnerable to harm during crises, yet child public health expertise is limited in humanitarian settings and outcomes and impact data are lacking. This review characterises child public health indicators that are routinely collected, required by donors, and recommended for use in fragile, conflict-affected, and vulnerable (FCV) settings. We conducted database and grey literature searches and collected indicators from technical agencies, partnerships, donors, and nongovernmental organisations providing child public health services in FCV settings.
View Article and Find Full Text PDFThe Los Angeles-B esophagitis is a conclusive diagnostic evidence for gastroesophageal reflux disease: the validation of Lyon Consensus 2.0.
Gastroenterol Rep (Oxf)
March 2025
Department of Gastroenterology, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou, Guangdong, P. R. China.
Background And Aims: Recently, Lyon Consensus 2.0 recommended Los Angeles (LA)-B esophagitis as conclusive evidence and LA-A esophagitis as borderline evidence for gastroesophageal reflux disease (GERD). This study aimed to investigate the diagnostic value of LA-B and LA-A esophagitis.
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