Diagnostic approach to hepatic vascular lesions: a paediatric perspective.

Histopathology

Department of Pathology, University of California San Francisco, San Francisco, CA, USA.

Published: December 2024

AI Article Synopsis

  • - The evaluation of liver vascular lesions in children is complex due to inconsistent terminology, rare samples, and similar features among different lesions, making diagnosis challenging.
  • - This review emphasizes the need for using the International Society for the Study of Vascular Anomalies (ISSVA) classification to more accurately categorize these lesions.
  • - The text discusses specific cases, including pediatric liver tumors like hepatic infantile and congenital hemangiomas, as well as vascular malformations linked to syndromes and potential complications.

Article Abstract

The pathological evaluation of hepatic vascular lesions in children requires special consideration. Inconsistent terminology, rarity of pathology specimens and overlapping pathological features between various lesions may pose a serious diagnostic challenge. In this review, we highlight the importance of using the International Society for the Study of Vascular Anomalies (ISSVA) classification scheme to characterise these lesions. Selected entities are discussed, including hepatic vascular tumours exclusively seen in the paediatric age group, hepatic infantile haemangioma and hepatic congenital haemangioma. Vascular malformations, with emphasis on their syndromic associations (venous malformation in blue rubber bleb naevus syndrome) and complications (hepatocellular nodules in Abernethy malformation) are also covered.

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Source
http://dx.doi.org/10.1111/his.15250DOI Listing

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