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Potential of non-Western medicines in chemoradiotherapy for cervical cancer.
World J Clin Cases
January 2025
Department of Radiation Oncology, Faculty of Medicine, Yamagata University, Yamagata 990-9585, Japan.
This editorial explores the potential integration of non-Western medicine into radiotherapy for cervical cancer. While radiotherapy remains a radical treatment for cervical cancer, its associated toxicity and decline in quality of life can significantly impact patients' lives. Currently, most treatments are supportive, with no specific treatment options available in Western medicine.
View Article and Find Full Text PDF"Three Sides to Every Story": Living the Patient, Carer and Staff Experience of COVID.
Glob Qual Nurs Res
January 2025
Manchester University NHS Foundation Trust, Manchester, United Kingdom.
In 2020, the UK's National Health Service (NHS) braced itself for the challenge of the COVID pandemic. Older, frail adults were among those at highest risk for morbidity and mortality. This study aimed to capture the lived experiences of patients, families/carers and staff on a COVID ward.
View Article and Find Full Text PDFTherapeutic Intervention for Trunk Control Impairments in Central Nervous System Disorders: A Comprehensive Review of Methods and Efficacy.
Prog Rehabil Med
January 2025
Department of Rehabilitation Medicine, Osaka Medical and Pharmaceutical University, Osaka, Japan.
Objectives: Trunk control involves multiple brain regions related to motor control systems. Therefore, patients with central nervous system (CNS) disorders frequently exhibit impaired trunk control, decreasing their activities of daily living (ADL). Although some therapeutic interventions for trunk impairments have been effective, their general effects on CNS disorders remain unclear.
View Article and Find Full Text PDFThe Impact of Executive Function on Retention and Compliance in Physical Therapy in Veterans.
Arch Rehabil Res Clin Transl
December 2024
New England Geriatric Research, Education and Clinical Center, VA Boston Healthcare System, Boston MA.
Objective: To examine retention and compliance to a novel physical therapy (PT) treatment among Veterans with and without executive function deficits (EFD+/EFD-).
Design: This study was a preplanned secondary analysis of an ongoing randomized controlled trial.
Setting: Outpatient PT at VA Boston Healthcare System.
Neuron-derived extracellular vesicles as a liquid biopsy for brain insulin dysregulation in Alzheimer's disease and related disorders.
Alzheimers Dement
January 2025
Department of Internal Medicine-Gerontology and Geriatric Medicine, Wake Forest University School of Medicine, Winston-Salem, North Carolina, USA.
Extracellular vesicles (EVs) have emerged as novel blood-based biomarkers for various pathologies. The development of methods to enrich cell-specific EVs from biofluids has enabled us to monitor difficult-to-access organs, such as the brain, in real time without disrupting their function, thus serving as liquid biopsy. Burgeoning evidence indicates that the contents of neuron-derived EVs (NDEs) in blood reveal dynamic alterations that occur during neurodegenerative pathogenesis, including Alzheimer's disease (AD), reflecting a disease-specific molecular signature.
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