AI Article Synopsis
- The study investigates how distal bypass surgery affects tissue blood pressure in direct (DRA) and indirect (IRA) revascularized angiosomes in patients with chronic limb-threatening ischemia (CLTI).
- A total of 29 limbs from 27 CLTI patients underwent repeated skin perfusion pressure (SPP) measurements before and after surgery, showing improvements in tissue blood flow for both DRA and IRA.
- The findings suggest that distal bypass surgery enhances tissue blood flow throughout the foot, not just in the connected angiosomes.
Article Abstract
Distal bypass surgery's effect on tissue blood pressure beyond a focal angiosome remains debated. This study assessed tissue blood pressure in both direct revascularized angiosome (DRA) and indirect revascularized angiosome (IRA) after bypass surgery, utilizing repeated skin perfusion pressure (SPP) measurements. Twenty-nine limbs in 27 chronic limb-threatening ischemia (CLTI) patients (22 males and five females, age: 70.2 ± 9.3 years) who received distal bypass surgery were enrolled. SPP measurements were conducted for the DRA and IRA at 10 time intervals, encompassing both preoperative and postoperative periods of every 3-5 days until 30 days. In total, 486 SPP measurements were collected from 58 measurement sites, and the transition of the SPP at the DRA was 35.4-62.5-59.5-70.2-58.2-62.2-63.1-63.6-63.8-73.4 mmHg and IRA was 29.4-53.4-53.7-58.8-51.3-63.1-47.9-62.1-57.6-61.0 mmHg. No significant differences were observed between SPP at the DRA and IRA. Fifteen wounds on the DRA (63%) and five on the IRA (100%) healed. Distal bypass improves SPP in both direct and IRAs of CLTI patients. These data indicated distal bypass improves tissue blood flow at entire foot regardless of angiosomes.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11196174 | PMC |
| http://dx.doi.org/10.3400/avd.oa.23-00105 | DOI Listing |
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