We report an immunocompromised patient with a complex cutaneous leishmaniasis (CL) who suffered from singular bone involvement of the little left toe due to Leishmania (L.) infantum infection. The diagnosis was confirmed by positive polymerase chain reaction (PCR) testing in skin and bone tissue. The patient was successfully treated with miltefosine. In immunocompromised patients with CL, extracutaneous manifestations should always be ruled out. This is the first case report describing osseous involvement in CL due to Leishmania infantum.
Download full-text PDF |
Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11300559 | PMC |
| http://dx.doi.org/10.1007/s00105-024-05355-2 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Enhanced Detection of Leishmania Parasites in Microscopic Images Using Machine Learning Models.
Sensors (Basel)
December 2024
Facultad de Ingeniería, Pontificia Universidad Javeriana, Bogotá 110231, Colombia.
Cutaneous leishmaniasis is a parasitic disease that poses significant diagnostic challenges due to the variability of results and reliance on operator expertise. This study addresses the development of a system based on machine learning algorithms to detect spp. parasite in direct smear microscopy images, contributing to the diagnosis of cutaneous leishmaniasis.
View Article and Find Full Text PDFExploring Pediatric Dermatology in Skin of Color: Focus on Dermoscopy.
Life (Basel)
December 2024
Institute of Dermatology, Department of Medical Area, University of Udine, 33100 Udine, Italy.
This literature review aims to comprehensively evaluate the clinical and dermoscopic presentations of common pediatric diseases among children with skin of color (SoC) while also addressing potential variations based on racial backgrounds. This review encompasses various conditions, such as nevi subtypes, viral infections, infestations, and inflammatory dermatoses, as well as hair diseases and abnormal vascular formations, occurring in pediatric populations. Overall, we identified 7 studies on nevi subtypes, 24 studies on skin infections, 6 on inflammatory dermatoses, 10 on hair diseases and disorders, and 14 on miscellaneous disorders that also satisfied our SoC- and race-specific criteria.
View Article and Find Full Text PDFBiomarker Insights: Evaluation of Presepsin, Apelin, and Irisin Levels in Cutaneous Leishmaniasis.
Diagnostics (Basel)
December 2024
Department of Dermtoology, Faculty of Medicine, Dicle University, 21280 Diyarbakir, Turkey.
: Cutaneous leishmaniasis (CL) is a skin disease caused by parasites. Presepsin, irisin, and apelin are biomarkers that are involved in the inflammatory response. The aim of this study was to investigate the association between serum levels of specific biomarkers, such as presepsin, apelin, and irisin, and the clinical features, location, number, and size of lesions in patients with CL.
View Article and Find Full Text PDFLeishmania sp. can affect the cardiovascular system of dogs - A systematic review of over 80 years.
Vet Parasitol
January 2025
Department of Veterinary Clinic and Surgery, Veterinary School, Federal University of Minas Gerais - UFMG, Belo Horizonte, Minas Gerais, Brazil; National Institute of Science and Technology in NanoBiopharmaceutics (INCT-Nanobiofar), Belo Horizonte, Minas Gerais, Brazil.
Cardiovascular involvement in Leishmania sp. infections still requires further elucidation, with cutaneous and organic changes being more frequently observed. The aim of this study was to conduct a systematic review of cardiovascular involvement in dogs with canine visceral leishmaniasis, considering a publication span of over 80 years.
View Article and Find Full Text PDFLeishmania (Leishmania) amazonensis and Leishmania (Leishmania) infantum sialic acids enhance macrophage infection.
Cell Biol Int
January 2025
Laboratory of Leishmaniasis, Department of Parasitology, Institute of Biomedical Sciences, University of São Paulo, São Paulo, Brazil.
Leishmaniases affect millions of people around the world, caused by Leishmania parasites. Leishmania are transmitted by female sandflies from Phlebotominae subfamily during their blood meals. In mammals, promastigotes are phagocytosed mainly by macrophages, differentiate into amastigotes and multiply.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!