Chikungunya fever (CKF), a neglected tropical disease caused by the chikungunya virus, manifests with skin pigmentary changes in a significant portion of people. A myriad of pigmentary alterations in individuals with CKF have been documented in the literature. This review highlights the pathogenesis, clinical features, histopathology, diagnosis and treatment of CKF-associated pigmentation. Notable presentations include the 'Chik sign' often seen in neonates and children. Treatment involves reassurance and topical agents for persistent pigmentation. Understanding these pigmentary changes is crucial for accurate diagnosis and management, facilitating improved patient outcomes. Further research is warranted to fully elucidate the underlying mechanisms and optimize therapeutic strategies.
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Article Synopsis
- * The review highlights how skin aging can lead to pigmentary disorders, such as hyperpigmentation (like melasma) and hypopigmentation (like vitiligo).
- * It discusses the mechanisms behind how aging affects skin pigmentation and proposes possible treatment strategies for managing skin aging and related pigmentary issues.
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