AI Article Synopsis
- Nitrous oxide is used medically for anesthesia, in food as a propellant, and recreationally for its euphoric effects.
- Three cases were reported where nitrous oxide misuse led to severe vitamin B12 deficiency, accompanied by distinctive symptoms like palmar calluses and frostbite.
- These symptoms can help doctors identify nitrous oxide use and diagnose potential toxicity more quickly.
Article Abstract
Nitrous oxide is used medically as an anesthetic agent; in the food industry as a propellant for condiments; and recreationally for its euphoric and dissociative effects. We report three cases of nitrous oxide misuse causing severe, symptomatic cobalamin (vitamin B12) deficiency in which signs of nitrous oxide use per se, as well as signs of toxicity, were observed, including characteristic palmar calluses over the metacarpal heads, and frostbite. These signs may assist clinicians in the recognition of nitrous oxide use and the timely diagnosis of nitrous oxide toxicity.
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| http://dx.doi.org/10.1080/10550887.2024.2369744 | DOI Listing |
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