AI Article Synopsis
- Colorectal cancer (CRC) hospitalizations increased from 2010 to 2019, with a shift in demographics showing a slightly younger average age and a predominance of male and White patients.
- Inpatient mortality rates decreased slightly during this period, with higher mortality observed in men and Blacks, while only Whites experienced a significant decline in mortality.
- The study underscores the influence of sociodemographic factors on CRC outcomes, advocating for targeted interventions to improve equity in care and encourage further research to enhance patient survival.
Article Abstract
Background: Colorectal cancer (CRC) poses a significant burden on healthcare systems globally. Sociodemographic factors intricately influence CRC epidemiology, yet their impact on inpatient care remains underexplored. This study aimed to assess trends in CRC hospitalization and the effect of sociodemographic factors on outcomes of CRC patients.
Methods: A retrospective longitudinal analysis was conducted using data from the Healthcare Cost and Utilization Project National Inpatient Sample. Trends in CRC admissions were assessed, stratified by sociodemographic variables. Disparities in hospital-associated outcomes were examined. Statistical methods included multivariable regression and joinpoint regression analysis.
Results: The prevalence of CRC hospitalizations uptrended from 760 per 100,000 hospitalizations in 2010 to 841 per 100,000 hospitalizations in 2019 ( trend < 0.001). The mean age decreased from 67 to 66 years ( < 0.001). Male gender and White race were predominant across the study period. Inpatient mortality decreased from 4.5% in 2010 to 4.16% in 2019 ( trend = 0.033). On sex subgroup analysis, men had a significantly higher mortality rate ( = 0.034). Racially, Blacks had the highest mortality rate ( = 0.550) and only Whites showed a significant decline in mortality over the study period ( = 0.003). Hospitalization length decreased while total hospital charges increased.
Conclusion: Our study highlights sociodemographic disparities in CRC outcomes, emphasizing the need for targeted interventions to address inequity in screening, diagnosis, and treatment. Continued research is needed to inform effective healthcare practices in mitigating these disparities and improving survival outcomes.
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|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11188818 | PMC |
| http://dx.doi.org/10.1080/08998280.2024.2346404 | DOI Listing |
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