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Intraoperative extracorporeal membrane oxygenation (ECMO) support during thoracic surgery for high-risk patients has most commonly been performed and reported in open cases. Minimally invasive thoracic surgery with venoarterial (VA) ECMO support has not been reported before. We report a successful case of VA ECMO-assisted robotic right upper lobectomy in a hemodynamically labile patient with severe bullous emphysema, hypoxia-induced severe pulmonary hypertension, and cor pulmonale.

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Time-efficient HPLC Validation Methodology for the Qualitative Analysis of 68Ga PSMA-11 in Routine Clinical Usage under Isocratic Method.

Indian J Nucl Med

November 2024

Department of Nuclear Medicine and Molecular Imaging, Homi Bhabha Cancer Hospital and Mahamana Pandit Madan Mohan Malaviya Cancer Centre, Tata Memorial Centre, Homi Bhabha National Institute, Varanasi, Uttar Pradesh, India.

Background: Prostate-specific membrane antigen (PSMA) has shown to be a promising agent for prostate cancer imaging under PET-CT. With the automation in radiolabeling with 68Ga, using iTG 68Ge/68Ga generator, it has helped introduce various new diagnostic agents and achieve good manufacturing practices (GMP) simultaneously. However, before any radiopharmaceutical is put into clinical usage, it should always be checked for its radiochemical purity and other quality parameters before injecting in the patient.

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Infant Cardiac Rhabdomyoma With Incessant Arrhythmia: Role of Tumor Debulking and Margin Cryoablation.

Ann Thorac Surg Short Rep

December 2023

Department of Pediatric and Congenital Heart Surgery, Cleveland Clinic Children's Hospital and Heart, Vascular, and Thoracic Institute, Cleveland Clinic, Cleveland, Ohio.

We describe the management of a 4-month-old girl (5.0 kg) who presented with atrial arrhythmias in the setting of cardiac rhabdomyomas. Despite maximal medical therapy and extracorporeal membrane oxygenation support, atrial arrhythmias persisted.

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Background: The expanded polytetrafluoroethylene (ePTFE) valved conduit (VC) has been reported for pulmonary valve replacement (PVR). The purpose of this study was to review long-term outcomes of our trileaflet ePTFE VC.

Methods: This multicenter study was performed with institutional review board approval from each institution.

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The proteomic response of to amphotericin B (AmB) reveals the involvement of the RTA-like protein RtaA in AmB resistance.

Microlife

December 2024

Department of Molecular and Applied Microbiology, Leibniz Institute for Natural Product Research and Infection Biology, Hans Knöll Institute (HKI), Adolf-Reichwein-Str. 23, 07745 Jena, Germany.

The polyene antimycotic amphotericin B (AmB) and its liposomal formulation AmBisome belong to the treatment options of invasive aspergillosis caused by . Increasing resistance to AmB in clinical isolates of species is a growing concern, but mechanisms of AmB resistance remain unclear. In this study, we conducted a proteomic analysis of exposed to sublethal concentrations of AmB and AmBisome.

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