Sinonasal malignant tumors are a group of uncommon malignancies that account for less than 1% of all tumors. These tumors often involve the maxillary sinus and nasal cavity, with less cumulative incidence in the ethmoidal sinus, sphenoidal sinus, and frontal sinus. The lack of consensus on the management of sinonasal malignancies is due to their rarity, diagnostic challenges, and the heterogeneity of treatments. In this paper, we present a case of endoscopic-assisted medial canthus incision combined with radiotherapy in the treatment of sinonasal malignant tumors, with the aim of providing valuable insights to clinicians on the management of these tumors.
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http://dx.doi.org/10.1186/s12957-024-03448-9 | DOI Listing |
J Craniofac Surg
March 2025
Maxillofacial Surgery Unit, Department of Neurosciences, Reproductive and Odontostomatological Sciences, University of Naples Federico II, Naples, Italy.
Eyelid defects, particularly those affecting the medial canthus, present intricate challenges for reconstructive surgeons due to the complex anatomy and functional significance of the region. This article presents our management of an 87-year-old patient with medial canthal basal cell carcinoma, highlighting the successful management of such defects through a single-stage reconstruction technique involving a skin graft supported by a synthetic dermal matrix (MatriDerm). The utilization of this approach resulted in favorable outcomes, including clear margins on histological examination and stable esthetic results at 1-year follow-up, emphasizing its efficacy in addressing medial canthal defects secondary to basal cell carcinoma excision.
View Article and Find Full Text PDFDermatol Surg
March 2025
Department of Dermatology, University of New Mexico, Albuquerque, New Mexico.
Invest Ophthalmol Vis Sci
March 2025
Department of Radiology, Fuyong People's Hospital, Baoan District, Shenzhen, Guangdong, China.
Purpose: The accurate determination of the etiology and location of lacrimal passage obstruction is key to treatment. However, the main assessments for lacrimal passage are invasive and have limited value. This study aimed to analyze the causes of obstruction of the lacrimal passage and investigate the diagnostic value of magnetic resonance dacryocystography (MRD).
View Article and Find Full Text PDFFront Immunol
March 2025
Department of Ophthalmology, West China Hospital of Sichuan University, Chengdu, Sichuan, China.
Objective: This study aimed to investigate the expression condition of a proliferation-inducing ligand (APRIL) in lacrimal gland lesions of patients with IgG4-associated ophthalmic diseases (IgG4-ROD) and mucosa-associated lymphoid tissue (MALT) lymphoma.
Patients And Methods: Fifteen patients with IgG4-ROD, 3 with MALT lymphoma, and 1 with elevated IgG4 with lacrimal gland lesions, treated in West China Hospital of Sichuan University from April 2022 to November 2023, were included. Immunofluorescence staining was used to detect the expression of APRIL in the specimen of lacrimal gland.
Invest Ophthalmol Vis Sci
March 2025
Xiamen University affiliated Xiamen Eye Center; Fujian Provincial Key Laboratory of Ophthalmology and Visual Science; Eye Institute of Xiamen University; School of Medicine, Xiamen University, Xiamen, Fujian, China.
Purpose: To investigate the ocular surface changes during progress of the Sjögren's Syndrome (SS), using a previously described IL14α transgenic mice (IL14α TG) SS model.
Methods: The ocular surface of IL14α TG and C57BL/6 wild-type (WT) female mice were evaluated at the age of six, nine, 12, 15, and 18 months. Slit lamp microscopy observation, Oregon green dextran staining, Schirmer test, and periodic-acid-Schiff staining were assessed.
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