Sleep regulation and host genetics.

Adv Genet

Institut Nacional d'Educació Física de Catalunya (INEFC), Centre de Lleida, Universitat de Lleida (UdL), Lleida, Spain.

Published: June 2024

AI Article Synopsis

  • This chapter examines sleep-related phenotypes, focusing on those common in the population and influenced by lifestyle, such as sleep quality, insomnia, and daytime sleepiness.
  • It emphasizes the multifactorial nature of sleep regulation while setting aside less common sleep disorders and topics with insufficient evidence for practical solutions.
  • The relationship between sleep quality and circadian rhythms is mentioned, but in-depth exploration of circadian rhythm regulation is reserved for a separate chapter.

Article Abstract

Due to the multifactorial and complex nature of rest, we focus on phenotypes related to sleep. Sleep regulation is a multifactorial process. In this chapter, we focus on those phenotypes inherent to sleep that are highly prevalent in the population, and that can be modulated by lifestyle, such as sleep quality and duration, insomnia, restless leg syndrome and daytime sleepiness. We, therefore, leave in the background those phenotypes that constitute infrequent pathologies or for which the current level of scientific evidence does not favour the implementation of practical approaches of this type. Similarly, the regulation of sleep quality is intimately linked to the regulation of the circadian rhythm. Although this relationship is discussed in the sections that require it, the in-depth study of circadian rhythm regulation at the molecular level deserves a separate chapter, and this is how it is dealt with in this volume.

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Source
http://dx.doi.org/10.1016/bs.adgen.2024.02.002DOI Listing

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