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Immunology in corneal transplantation-From homeostasis to graft rejection.
Transplant Rev (Orlando)
January 2025
Laboratory of Ocular Immunology, Transplantation, and Regeneration, Schepens Eye Research Institute of Massachusetts Eye and Ear, Department of Ophthalmology, Harvard Medical School, Boston, MA, USA. Electronic address:
Immunology depends on maintaining a delicate balance within the human body, and disruptions can result in conditions such as autoimmune diseases, immunodeficiencies, and hypersensitivity reactions. This balance is especially crucial in transplantation immunology, where one of the primary challenges is preventing graft rejection. Such rejection can lead to organ failure, increased patient mortality, and higher healthcare costs due to the limited availability of donor tissues relative to patient needs.
View Article and Find Full Text PDFTolerance in Heart Transplantation: The Cost of Achieving the Holy Grail of Transplant.
Transplantation
January 2025
Division of Transplant Surgery, Department of Surgery, Stritch School of Medicine, Loyola University Chicago, Maywood, IL.
Correction of Multispectral Singlet Oxygen Luminescent Dosimetry (MSOLD) for Tissue Optical Properties in Photofrin-Mediated Photodynamic Therapy.
Antioxidants (Basel)
November 2024
Department of Radiation Oncology, University of Pennsylvania, Philadelphia, PA 19104, USA.
The direct detection of singlet-state oxygen (O) constitutes the holy grail dosimetric method for type-II photodynamic therapy (PDT), a goal that can be quantified using multispectral singlet oxygen near-infrared luminescence dosimetry (MSOLD). The optical properties of tissues, specifically their scattering and absorption coefficients, play a crucial role in determining how the treatment and luminescence light are attenuated. Variations in these properties can significantly impact the spatial distribution of the treatment light and hence the generation of singlet oxygen and the detection of singlet oxygen luminescence signals.
View Article and Find Full Text PDFIntrathymic alloantigen expression-the Holy Grail or reinventing the wheel?
Cell Res
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Department of Surgery, University of Cambridge, Cambridge, UK.
Association between biomass cooking fuels and prevalence of tuberculosis among households: a cross-sectional study from 2019 - 2021 in India.
BMC Public Health
December 2024
Department of Chemistry, College of Natural and Computational Sciences, Wollega University, P.O. Box 395, Nekemte, Ethiopia.
Background: Indoor air pollution (IAP) is the major contributor (26%) to TB, in addition to other socioeconomic and environmental factors. It occurs in most developing countries like India, where people rely on the combustion of biomass-based solid fuels (low combustion efficiency and high pollution emissions) due to the prevailing socio-economic conditions. However, this cause-and-effect relationship between TB and IAP has not been studied much.
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