Objectives: To investigate the four-year clinical outcome and marginal bone loss around narrow-diameter implants in patients with uncontrolled diabetes mellitus type 2 (T2DM) and normo-glycemic individuals.
Materials And Methods: In 11 T2DM patients with a concentration of glycated hemoglobin (HbA1C) > 6.5% (test group) and 15 normoglycemic patients (HbA1C < 6.0%; control group), one narrow-diameter tissue level implant, placed in the posterior maxilla or mandible, was investigated. The clinical parameters probing depth (PD), bleeding on probing (BOP), attachment loss (CAL), recession, and papilla bleeding index (PBI) were assessed manually after 24 and 48 months of function. The paired digital periapical radiographs were analyzed regarding the change in marginal bone level (MBL) from baseline to 48 months post-op. The technical complications were recorded.
Results: In the T2DM group, 11 patients were available for follow-ups. The overall implant survival rate after 48 months was 100%. The differences in means for the clinical parameters and the MBL between the T2DM and normo-glycemic patients for the observation period were statistically non-significant. No technical complications were recorded.
Conclusions: The study demonstrated an encouraging clinical outcome with ND implants in patients with uncontrolled T2DM compared to non-diabetics after 48 months' post loading.
Clinical Relevance: Patients with HbA1C > 6.5% may benefit from the treatment with narrow-diameter implants by avoiding complex surgical interventions with augmentation procedures. REGISTRATION NUMBER (CLINICALTRIALS.GOV): NCT04630691.
Download full-text PDF |
Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11192651 | PMC |
| http://dx.doi.org/10.1007/s00784-024-05786-0 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Ephemeral Diabetes After COVID-19 Vaccination.
JCEM Case Rep
January 2025
Department of Internal Medicine, Division of Endocrinology and Diabetology, Gävle Hospital, University of Gävle, Gävle SE-80324, Sweden.
We report a case of new-onset, nonautoimmune, nonketotic, and noninsulinopenic type 2-like diabetes in a previously normoglycemic middle-aged man debuting after vaccination against COVID-19. This was not a mild or short-lived glucose intolerance, but severe and long-standing hyperglycemia with a high glycated hemoglobin level. However, the course of the diabetes was highly atypical and surprising in that it spontaneously disappeared after a few months and did not recur despite the patient being off all antidiabetic drugs for several months and without any changes in body weight or lifestyle.
View Article and Find Full Text PDFAssociation between serum copeptin levels and non-obese normoglycemic polycystic ovary syndrome: A case control study.
Turk J Obstet Gynecol
December 2024
Hitit University Faculty of Medicine, Department of Obstetrics and Gynecology, Çorum, Turkey.
Objective: Copeptin is a glycopeptide that increases under stress and is present in polycystic ovary syndrome (PCOS) patients with metabolic system disorders. We examined the relationship between copeptin and reproductive function in patients with normoglycemic PCOS with anovulatory cycles and normal weight.
Materials And Methods: Women with unexplained infertility (n=52) and women with PCOS (n=57) were included in the study.
Health-related fitness benefits following concurrent high-intensity interval training and resistance training in patients with type-1 diabetes or type-2 diabetes.
Front Physiol
November 2024
Cardio-Pulmonary Exercise Laboratory, Faculty of Motor Sciences, Université Libre de Bruxelles, Brussels, Belgium.
Introduction: Cardiorespiratory fitness (CRF), as assessed by VOpeak, along with metabolic and cardiovascular health indices, represents the strongest predictors of survival. However, it remains unclear whether concurrent high-intensity interval training (HIIT) and resistance training (RT) can similarly enhance these health markers in patients with type-1 diabetes (T1D) or type-2 diabetes (T2D) compared to healthy individuals.
Methods: Adults with uncomplicated T1D or T2D and healthy normoglycemic controls matched for sex and age (HC1 and HC2) performed 3 training sessions/week of concurrent HIIT and RT for 12 weeks.
Correlation between admission hyperglycemia and postoperative pneumonia after hip fracture surgery: A propensity score-matched study.
Sci Rep
December 2024
Department of Orthopedics, Zigong First People's Hospital, No. 42, Yizhi Road, Shangyihao Street, Zigong, 643000, Sichuan Province, People's Republic of China.
The association between admission hyperglycemia and postoperative pneumonia is unclear in hip fracture patients. We investigated the relationship between admission hyperglycemia and postoperative pneumonia after hip fracture surgery. This retrospective study analyzed data from 1,267 geriatric patients admitted for hip fractures.
View Article and Find Full Text PDF[SGLT2 inhibitors - A novel treatment for congestive heart failure and chronic kidney disease].
Laeknabladid
December 2024
MD, MS. Sahlgrenska University Hospital, Gothenburg, Sweden.
Article Synopsis
- - SGLT2 inhibitors block transporters in the kidneys, which increases sodium and glucose excretion, leading to lower blood sugar levels, improved blood pressure, and weight loss.
- - These medications have shown protective effects for the heart and kidneys, reducing the risk of cardiovascular death, hospitalization due to heart failure, and progression to advanced kidney disease.
- - While SGLT2 inhibitors are generally safe and do not raise the risk of low blood sugar or acute kidney injury, they can lead to rare but serious side effects, like normoglycemic ketoacidosis and Fournier's gangrene, that require medical awareness.
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!