Somatic and sympathetic tones fluctuate together seamlessly across daily behaviors. In this issue of Cell, Zhang et al. describe populations of spinal projecting neurons in the rostral ventromedial medulla (rVMM) that harmonize somatic motor function and sympathetic activation. The coordinated regulation plays a vital role in supporting behaviors associated with various arousal states.
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http://dx.doi.org/10.1016/j.cell.2024.05.019 | DOI Listing |
BMC Cancer
August 2024
Department of Radiation Oncology, The First Medical Center of PLA General Hospital, Beijing, 100853, China.
Cell
June 2024
Department of Molecular & Cell Biology, Howard Hughes Medical Institute, University of California Berkeley, Berkeley, CA, USA. Electronic address:
Somatic and sympathetic tones fluctuate together seamlessly across daily behaviors. In this issue of Cell, Zhang et al. describe populations of spinal projecting neurons in the rostral ventromedial medulla (rVMM) that harmonize somatic motor function and sympathetic activation.
View Article and Find Full Text PDFJ Neurol Neurosurg Psychiatry
September 2022
CORe, Department of Medicine, The University of Melbourne, Melbourne, Victoria, Australia
Background: Early recognition of markers of faster disability worsening in paediatric-onset multiple sclerosis (MS) is a key requisite of personalised therapy for children with MS at the earliest possible time.
Objective: To identify early predictors of rapid disability accrual in patients with paediatric-onset MS.
Methods: Using the global MSBase registry, we identified patients who were <18 years old at the onset of MS symptoms.
Front Oncol
March 2022
Department of Radiation Oncology, The First Medical Center of the Chinese PLA General Hospital, Beijing, China.
Purpose: The purpose of this study was to evaluate and explore the difference between an atlas-based and deep learning (DL)-based auto-segmentation scheme for organs at risk (OARs) of nasopharyngeal carcinoma cases to provide valuable help for clinical practice.
Methods: 120 nasopharyngeal carcinoma cases were established in the MIM Maestro (atlas) database and trained by a DL-based model (AccuContour), and another 20 nasopharyngeal carcinoma cases were randomly selected outside the atlas database. The experienced physicians contoured 14 OARs from 20 patients based on the published consensus guidelines, and these were defined as the reference volumes (V).
Nat Commun
January 2022
Institut Curie, PSL Research University, CNRS UMR144, 75005, Paris, France.
Primary microcephaly and megalencephaly are severe brain malformations defined by reduced and increased brain size, respectively. Whether these two pathologies arise from related alterations at the molecular level is unclear. Microcephaly has been largely associated with centrosomal defects, leading to cell death.
View Article and Find Full Text PDFEnter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!