Validation of the GERAADA score to predict 30-day mortality in acute type A aortic dissection in a single high-volume aortic centre.

Eur J Cardiothorac Surg

Department of Cardiothoracic Surgery, Manchester Royal Infirmary, Manchester, UK.

Published: July 2024

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http://dx.doi.org/10.1093/ejcts/ezae244DOI Listing

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Objective: In literature, various risk scores have been described to predict in-hospital mortality of patients undergoing surgery for acute type A dissection. We want to evaluate which factors are most correlated with a negative outcome and testing the validity of the current scores in literature analyzing our experience of over 20 years in the surgery of type A aortic dissections.

Materials And Methods: A total of 324 patients were included in the study.

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Article Synopsis
  • Researchers validated four different mortality prediction scores for patients undergoing surgery for type A acute aortic dissection (TAAD) in a large study across 10 European centers from 2000 to 2020.
  • A total of 1,895 patients were analyzed, revealing 30-day mortality at 21.7% and in-hospital mortality at 22.5%.
  • The GERAADA score outperformed the other scores in predicting both early and 1-year mortality, but overall, none of the scores provided reliable predictions in terms of discrimination and calibration.
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Objectives: This study aimed to evaluate employing the German Registry of Acute Aortic Dissection Type A (GERAADA) score to predict 30-day mortality in an aortic centre in the USA.

Methods: Between January 2010 and June 2021, 689 consecutive patients underwent surgery for acute type A dissection at a single institution. Excluded were patients with missing clinical data (N = 4).

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