AI Article Synopsis
- Systemic sclerosis (SSc) is a complex autoimmune disease that affects various body systems, leading to symptoms like fibrosis and immune system problems, and it’s important for allergists to understand its features.
- Recent advancements in SSc management have made significant progress over the last decade, focusing on tailored strategies for symptoms affecting the skin, airways, gastrointestinal tract, and blood vessels.
- Early intervention and referrals to specialized care can enhance patient outcomes and quality of life, but there is still a need for improved biomarkers and more effective targeted treatments.
Article Abstract
Purpose Of Review: Systemic sclerosis (SSc) is a chronic, multisystem, autoimmune disease characterized by fibrosis, vasculopathy and immune system dysregulation. We provide a comprehensive review of features of systemic sclerosis that can potentially present to the allergist.
Recent Findings: A thorough understanding of the management options is crucial for clinicians involved in the care of patients with SSc to optimize clinical outcomes. Management of systemic sclerosis has drastically changed in the last decade and continues to evolve. This review provides an overview of management strategies for the various symptoms including skin, upper and lower airway, gastrointestinal and vascular manifestations. Institution of treatment early in the disease, including referral to rheumatology or specialized scleroderma centers, can help to both prevent and manage disease complications, and improve patient quality-of-life. While the landscape of systemic sclerosis management has evolved, we continue to recognize that there is still a need for better biomarkers and targeted therapies.
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| http://dx.doi.org/10.1007/s11882-024-01155-9 | DOI Listing |
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