A 34-year-old male, with no history of known previous disease, employed at a ginger farm in South India, presented with a four-day history of high-grade fever and headache. Initially, he received symptomatic treatment but was referred due to hypotension and persistent fever. Investigations showed leucocytosis, thrombocytopenia, abnormal liver function tests, renal dysfunction, and elevated C-reactive protein. Positive results were obtained for  immunoglobulin M (IgM) and scrub typhus IgM tests, indicating a coinfection, reported rarely from this region. Timely clinical suspicion, prompt laboratory diagnosis, and early treatment with doxycycline and broad-spectrum antibiotics are crucial to prevent complications and fatal outcomes in such coinfections.

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11187789PMC
http://dx.doi.org/10.7759/cureus.60732DOI Listing

Publication Analysis

Top Keywords

scrub typhus
8
double blow
4
blow tropics
4
tropics case
4
case concurrent
4
concurrent leptospirosis
4
leptospirosis scrub
4
typhus 34-year-old
4
34-year-old male
4
male history
4

Similar Publications

Background Objectives: Scrub typhus is an acute febrile zoonotic disease caused by the obligate intracellular gram-negative bacteria Orientia tsutsugamushi. Growing data over the last few years on the Indian subcontinent suggest that it is one of the most widespread but under-reported diseases. The study aimed to document the clinical and paraclinical profile and evaluate complications of scrub typhus in severe and nonsevere pediatric age groups.

View Article and Find Full Text PDF

Double-Stranded RNA-Based Method for Diagnosing Severe Fever with Thrombocytopenia.

J Clin Med

December 2024

Department of Internal Medicine, Division of Infectious Disease, Soonchunhyang University Hospital, Cheonan 31151, Republic of Korea.

: This study explores the potential of using elevated levels of blood double-stranded RNA (dsRNA) as a diagnostic tool for severe fever with thrombocytopenia syndrome (SFTS) infection. : Blood samples from SFTS patients were collected, dsRNA was purified, and total dsRNA expression was quantitatively analyzed using a spiropyran-based method. Comparative analysis was performed using blood samples from healthy individuals and scrub typhus patients with similar symptoms.

View Article and Find Full Text PDF

A case report of pediatric scrub typhus presenting as acalculous cholecystitis during the non-epidemic season without eschar.

Travel Med Infect Dis

January 2025

Second Department of Infectious Disease, Kunming Children's Hospital, Kunming, Yunnan, China; Yunnan Key Specialty of Pediatric Infection (Training and Education Program)/Kunming Key Specialty of Pediatric Infection, China; Faculty of Life Science and Technology, Kunming University of Science and Technology, Kunming, Yunnan, China. Electronic address:

View Article and Find Full Text PDF

Scrub typhus (ST) is an emerging public health concern in India. Despite being treatable, 20-30 % of acute febrile illnesses (AFI) progress to encephalitis in endemic regions. This study aimed to identify early markers for encephalitis development in children hospitalized with AFI and positive Orientia tsutsugamushi (Ots) serology.

View Article and Find Full Text PDF

Historical Overview of Tsutsugamushi Disease in Japan before World War II.

Infect Chemother

December 2024

Division of Infectious Diseases, Department of Internal Medicine, Inha University School of Medicine, Incheon, Korea.

Tsutsugamushi disease is a febrile mite-borne disease caused by . Before 1945, this disease had been prevalent in Niigata, Akita, and Yamagata prefectures for centuries, occurring in areas along major rivers in these prefectures every summer about a month after floods. The patients affected were farmers, possibly new settlers on reclaimed lands, who contracted the disease following bites of tiny red bugs.

View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!