Introduction And Importance: Seborrheic keratosis (SK) is a common benign epidermal tumor usually presenting as small, non-pigmented lesions on the skin. However, giant SK presenting as a pigmented variant is a rare occurrences, with limited documented cases in medical literature.
Case Presentation: Here, we present a case report of a 70 year old female patient with an unusual giant warty cutaneous lesion prompting excisional biopsy. Histopathological examination revealed pigmented proliferative basaloid cell and pseudohorn cysts, characteristic of SK. Notably, the lesion exhibited pigmentation, adding to the rarity of the giant forms of SK case.
Clinical Discussion: Giant pigmented seborrheic keratosis (GPSK) is an uncommon form that shares clinical and dermatoscopic features, frequently causing misdiagnosis as malignant melanoma.
Conclusion: Thus this report underscores the importance recognizing such atypical presentations of SK and highlights the need for histological evaluation to diagnose such variants.
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http://dx.doi.org/10.1016/j.ijscr.2024.109916 | DOI Listing |
Med J Malaysia
January 2025
Department of General Surgery, Saveetha Medical College and Hospital, Saveetha Institute of Medical and Technical Sciences (SIMATS), Saveetha University, Thandalam, Chennai, Tamil Nadu, India.
Seborrheic keratosis (SK) is a prevalent hyperkeratotic dermatological condition characterized by benign proliferation of epidermal keratinocytes, typically occurring in the middle to advanced stages of life. While the trunk is the primary site for lesions, they can also manifest on the extremities, face, and scalp. Although SK is typically benign, there can be morphological overlap with malignant skin lesions, necessitating meticulous differentiation for an accurate diagnosis.
View Article and Find Full Text PDFJ Cutan Pathol
December 2024
Department of Dermatology, The Affiliated Hospital of Qingdao University, Qingdao, China.
JID Innov
January 2025
Department of Dermatology, University of Texas Southwestern Medical Center, Dallas, Texas, USA.
Diagnostics (Basel)
November 2024
Ophthalmology Unit, Department of Medicine, Surgery and Neuroscience, University of Siena, 53100 Siena, Italy.
Dermatopathology (Basel)
October 2024
Dermatology Department, Doctor Jose Molina Orosa Hospital of Lanzarote, 35500 Arrecife, Spain.
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