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Analysis of pulmonary microecology and clinical characteristics of patients carrying human herpesvirus. | LitMetric

To investigate the impact of human herpes virus () carriage on lung microbiota, and its correlation with clinical features and laboratory indicators in patients. Retrospective analysis was conducted on 30 outpatient lung infection cases, which were divided into (n = 15) and non- (n = 15) groups. mNGS detected microbial composition. Microbial diversity and abundance were tested using Shannon and Chao1 indices. Their relationship with laboratory indicators were explored. Significant differences in microbial abundance and distribution were found between two groups (p < 0.05). Moreover, HHV group showed negative correlations (p < 0.05) between , , and basophil/eosinophil percentages. carriage impacts lung microbiota, emphasizing the need for clinicians to pay attention to reactivation in outpatient lung infection patients.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11323855PMC
http://dx.doi.org/10.1080/17460913.2024.2357994DOI Listing

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