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http://dx.doi.org/10.1016/j.xjtc.2024.03.018 | DOI Listing |
Am J Gastroenterol
December 2024
Department of Epidemiology/Department of Maternal, Child and Adolescent Health, School of Public Health, Cheeloo College of Medicine, Shandong University, Jinan, China.
Introduction: The clinical utility of metabolic dysfunction-associated steatotic liver disease (MASLD) in predicting subsequent subclinical cardiovascular damages in pediatric population remains poorly understood.
Methods: Data on 1,161 Chinese children aged 10-15 years were used to assess the longitudinal associations of MASLD with subsequent subclinical cardiovascular damages.
Results: Compared with relatively healthy children, children with MASLD had abnormal vascular and cardiac structures, along with reduced cardiac diastolic function at the 2-year follow-up.
Sleep
December 2024
Midwest Cardiovascular Institute, Naperville, Illinois, USA.
Central sleep apnea (CSA), a rare polysomnographic finding in the general population, is prevalent in certain cardiovascular conditions including systolic and diastolic left ventricular dysfunction, atrial fibrillation, coronary artery disease, carotid artery stenosis, stroke and use of certain cardiac-related medications. Polysomnographic findings of CSA with adverse cardiovascular impacts include nocturnal hypoxemia and arousals, which can lead to increased sympathetic activity both at night and in the daytime. Among cardiovascular diseases, CSA is most prevalent in patients with left ventricular systolic dysfunction; a large study of more than 900 treated patients has shown a dose dependent relationship between nocturnal desaturation and mortality.
View Article and Find Full Text PDFAlzheimers Dement
December 2024
Department of Radiology, Northwestern University, Chicago, IL, USA.
Background: Cerebral small vessel disease (cSVD) is a major cause of vascular dementia. Mounting evidence suggests that cSVD pathology is closely linked to vascular dysfunction of lenticulostriate arteries (LSAs). Arterial pulsatility, quantified by pulsatility index (PI), has been used as an indicator of vascular dysfunction.
View Article and Find Full Text PDFRadiol Cardiothorac Imaging
February 2025
From the University Medical Center Göttingen, Department of Cardiology and Pneumology, Georg-August University, Robert-Koch-Strasse 40, 37075 Göttingen, Germany (T.L., B.E.B., A. Schulz, R.E., K.R.R., K.T., G.H., M.P., A. Schuster); German Center for Cardiovascular Research (DZHK), Partner Site Göttingen, Göttingen, Germany (T.L., B.E.B., A. Schulz, R.E., K.R.R., K.T., G.H., M.P., A. Schuster); Department of Medicine, Cardiovascular Division, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, Mass (A. Schulz); Department of Cardiology, Campus Kerckhoff of the Justus-Liebig-University Giessen, Kerckhoff-Clinic, Bad Nauheim, Germany (S.J.B.); German Center for Cardiovascular Research (DZHK), Partner Site Rhine-Main, Bad Nauheim, Germany (S.J.B.); FORUM Radiology, Rosdorf, Germany (J.T.K.); Cluster of Excellence "Multiscale Bioimaging: from Molecular Machines to Networks of Excitable Cells" (MBExC), University of Göttingen, Göttingen, Germany (G.H.); and FORUM Cardiology, Rosdorf, Germany (A. Schuster).
Purpose To assess the prognostic implications of cardiac MRI-derived imaging markers in individuals with severe aortic stenosis (AS). Materials and Methods This prospective study (German Clinical Trials Register, DRKS00024479) enrolled individuals with severe AS who underwent cardiac MRI before transcatheter aortic valve replacement (TAVR) from January 2017 to March 2022. Image analyses included myocardial volumes, cardiac MRI feature tracking-derived left atrial (LA) and right atrial (RA) as well as left ventricular (LV) and right ventricular (RV) strain, myocardial T1 mapping, and late gadolinium enhancement analyses.
View Article and Find Full Text PDFAlzheimers Dement
December 2024
Centre de recherche de l'Institut Universitaire de Cardiologie et de Pneumologie de Québec, Quebec, QC, Canada.
Background: Our objective was to assess individual and joint relationships between various mesoscale indicators of brain health (e.g., neuronal, metabolic, and vascular integrity) and cognitive function.
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