AI Article Synopsis
- * A brain biopsy confirmed the diagnosis of acute disseminated encephalomyelitis (ADEM), specifically its aggressive form called acute hemorrhagic leukoencephalitis (AHLE).
- * Treatment with corticosteroids resulted in full recovery, emphasizing the need for awareness of AHLE in older patients and the potential for related eye conditions like retinal vasculitis.
Article Abstract
A 68-year-old Japanese man developed a fever, headache, hiccups, and altered consciousness. Brain magnetic resonance imaging (MRI) revealed a hemorrhagic lesion in the right temporal lobe and multiple high-intensity white matter lesions. A brain biopsy showed pathological findings consistent with acute disseminated encephalomyelitis (ADEM), suggesting a diagnosis of acute hemorrhagic leukoencephalitis (AHLE), an aggressive ADEM variant. The patient also developed myodesopsia and was diagnosed with retinal vasculitis, likely due to a hyperimmune state caused by AHLE. Corticosteroids enabled full recovery. Although AHLE is uncommon in elderly individuals, clinicians should be aware of its occurrence in this patient subgroup and recognize potential retinal manifestations associated with AHLE.
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| http://dx.doi.org/10.2169/internalmedicine.3518-24 | DOI Listing |
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