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Dynamic negative allosteric effect: regulation of catalysis multicomponent rotor speed. | LitMetric

Dynamic negative allosteric effect: regulation of catalysis multicomponent rotor speed.

Chem Commun (Camb)

Center of Micro and Nanochemistry and (Bio)Technology, Organische Chemie I, School of Science and Technology, University of Siegen, Adolf-Reichwein-Str. 2, D-57068 Siegen, Germany.

Published: July 2024

AI Article Synopsis

  • The nanorotor R1 operates at a frequency of 420 kHz and is made up of five components using three different interactions.
  • After modification, R2 was created, which consists of six components but operates at a lower frequency of 45 kHz.
  • The reduced speed of R2 slows down a three-component reaction by decreasing the release of the catalyst.

Article Abstract

Nanorotor R1 (420 kHz) was assembled from five components utilizing three orthogonal interactions. Post-modification at the distal position generated the advanced six component rotor R2 (45 kHz). The decrease in R2 speed leads to the inhibition of a three-component reaction by reducing catalyst release.

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Source
http://dx.doi.org/10.1039/d4cc02144dDOI Listing

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