The therapeutic landscape is experiencing a significant transformation with the development of strategies focused on the lysosomal degradation of extracellular targets. This innovative approach holds promise for combating many diseases by targeting and degrading pathogenic extracellular molecules. Pioneering advancements in this field introduce the concept of utilizing bifunctional compounds for the selective degradation of extracellular proteins and molecules. This Patent Highlight delves into the scientific principles, technological innovations, and therapeutic potential of these strategies, emphasizing their critical role in reshaping the future of medical treatments and highlighting their potential impact across a diverse range of disease contexts.
Download full-text PDF |
Source |
---|---|
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11181507 | PMC |
http://dx.doi.org/10.1021/acsmedchemlett.4c00180 | DOI Listing |
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!