Quartz Crystal Microbalances (QCMs) are versatile sensors employed in various fields, from environmental monitoring to biomedical applications, owing mainly to their very high sensitivity. However, the assessment of their metrological performance, including the impact of conditioning circuits, digital processing algorithms, and working conditions, is a complex and novel area of study. The purpose of this work is to investigate and understand the measurement errors associated with different QCM measurement techniques, specifically focusing on the influence of conditioning electronic circuits. Through a tailored and novel experimental setup, two measurement architectures-a Quartz Crystal Microbalance with dissipation monitoring (QCM-D) system and an oscillator-based QCM-R system-were compared under the same mechanical load conditions. Through rigorous experimentation and signal processing techniques, the study elucidated the complexities of accurately assessing QCM parameters, especially in liquid environments and under large mechanical loads. The comparison between the two different techniques allows for highlighting the critical aspects of the measurement techniques. The experimental results were discussed and interpreted based on models allowing for a deep understanding of the measurement problems encountered with QCM-based measurement systems. The performance of the different techniques was derived, showing that while the QCM-D technique exhibited higher accuracy, the QCM-R technique offered greater precision with a simpler design. This research advances our understanding of QCM-based measurements, providing insights for designing robust measurement systems adaptable to diverse conditions, thus enhancing their effectiveness in various applications.

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11174881PMC
http://dx.doi.org/10.3390/s24113401DOI Listing

Publication Analysis

Top Keywords

metrological performance
8
quartz crystal
8
measurement techniques
8
measurement systems
8
measurement
7
techniques
5
influence front-end
4
front-end electronics
4
electronics metrological
4
performance qcm
4

Similar Publications

Particle emissions study from tire sample with nano-silver tracer from different steps of its life cycle. A new approach to trace emissions of tire microparticles.

Sci Total Environ

January 2025

Direction Milieux et impacts sur le vivant, Institut National de l'Environnement Industriel et des Risques (INERIS), Verneuil en Halatte, France.

Emissions due to tires retread/repair and incineration are a cause of concern owing to the presence of nanoparticles in the products. The assessment exposure to humans hereto related is a challenge in an environmental context. The first object of this work is to develop a method to characterize the emission sources using online (counting and sizing) and offline measurements.

View Article and Find Full Text PDF

Behind the scenes of EQA - characteristics, capabilities, benefits and assets of external quality assessment (EQA).

Clin Chem Lab Med

January 2025

Canadian Microbiology Proficiency Testing Program (CMPT), Department of Pathology and Laboratory Medicine, University of British Columbia, Vancouver, Canada.

External quality assessment (EQA) enhances patient safety through the evaluation of the quality of laboratory-based and point of care testing. Regulatory agencies and accreditation organizations utilize the results and the laboratory's response to them as part of assessing the laboratory's fitness to practice. In addition, where EQA samples are commutable and the assigned value has been determined using reference measurement procedures (RMPs), EQA data contributes to the verification of metrological traceability of assays as part of the post-market surveillance of diagnostic (IVD) medical devices (IVD-MDs).

View Article and Find Full Text PDF

Establishing, evaluating and monitoring analytical quality in the traceability era.

Crit Rev Clin Lab Sci

January 2025

Department of Laboratory Medicine, Ludwik Rydygier Collegium Medicum in Bydgoszcz, Nicolaus Copernicus University in Torun, Bydgoszcz, Torun, Poland.

Poor analytical quality may be the bane of medical use of laboratory tests, and the fight against excessive analytical variability presents a daily struggle. Laboratories should prioritize the perspectives and needs of their customers (the patients and healthcare personnel). Among them, comparability of results from the same patient sample when measured by different laboratories using different diagnostic (IVD) medical devices is a logical priority to avoid result misinterpretation and potential patient harm.

View Article and Find Full Text PDF
Article Synopsis
  • - Commutable secondary certified reference materials (CRMs) are crucial for ensuring consistent results in medical lab tests, highlighting the need for their sustainable availability.
  • - The IFCC Working Group has released recommendations for assessing the commutability of these CRMs, although detailed studies can strain resources for producers.
  • - A new equivalence assessment method allows for comparing replacement CRMs with established ones, potentially reducing resource needs while ensuring reliability through the inclusion of representative clinical samples.
View Article and Find Full Text PDF

Covalent-Organic-Framework Enabled Efficient Three-dimensional K-storage via Electrolyte Solvation Manipulation.

ACS Appl Mater Interfaces

December 2024

Department of Chemistry and Materials Science, College of Science, Nanjing Forestry University, Nanjing 210037, P. R. China.

Covalent-organic-framework (COF) materials with a designable periodic framework have been expected as a kind of promising anode material for potassium ion batteries (PIBs). However, these materials suffer seriously from low capacity, poor rate performance, and slow reaction kinetics during the K-storage process, significantly limiting their widespread applications. Herein, a three-dimensional (3D) COF material denoted as CN-COF with a high N content and defined configuration as well as a graphite-like layer stacking structure was developed as a promising anode to realize efficient 3D K-storage performance with enhanced interfacial stability and reaction kinetics via an electrolyte chemistry compatibility strategy.

View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!