AI Article Synopsis
- - A novel dual-emission nanohybrid was created using green-synthesized carbon quantum dots (CDs) and glutathione-functionalized gold nanoclusters (GSH-AuNCs) to detect cefodizime sodium (CDZM).
- - The nanohybrid emits two fluorescence peaks at 458 nm and 569 nm upon excitation, with changes in fluorescence intensity upon CDZM addition serving as the basis for detection.
- - It demonstrated good linearity (1.0-1000.0 μM) and a low limit of detection (0.19 μM), successfully identifying CDZM in urine samples, indicating its potential for use in complex biological environments.
Article Abstract
A dual-emission ratio-fluorescent sensing nanohybrid based on Radix green-synthesized carbon quantum dots (CDs) and glutathione-functionalized gold nanoclusters (GSH-AuNCs) had been developed for the determination of cefodizime sodium (CDZM). The designed fluorescence nanohybrid had two significant fluorescence emission peaks at 458 nm and 569 nm when excited at 360 nm, which was attributed to the CDs and GSH-AuNCs. With the addition of CDZM, the fluorescence at 458 nm was slightly weakened while the fluorescence at 569 nm was enhanced obviously. Based on the relationship between the I/I fluorescence intensity ratio and the concentration of CDZM, the designed nanohybrid exhibited a good linearity range of 1.0-1000.0 μM and the limit of detection (LOD) was 0.19 μM. The method was finally applied in the detection of CDZM in urine, showing the potential applications in complicated biological samples.
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Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11172498 | PMC |
| http://dx.doi.org/10.3390/ijms25115971 | DOI Listing |
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