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Phosphodiesterase-5 Inhibitors Show Promise in Improving Survival for Patients With COPD Pulmonary Hypertension: One Step Further But There Is Still a Long Way to Go.
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Pulmonary Division, Lady Davis Carmel Medical Center, Faculty of Medicine Technion Institute of Technology, Haifa, Israel.
Impact of cardiovascular magnetic resonance in single ventricle physiology: a narrative review.
Cardiovasc Diagn Ther
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Department of Pediatric Cardiology, Royal Brompton Hospital, Guy's and St Thomas' NHS Foundation Trust, London, UK.
Background And Objective: Cardiovascular magnetic resonance (CMR) is a routine cross-sectional imaging modality in adults with congenital heart disease. Developing CMR techniques and the knowledge that CMR is well suited to assess long-term complications and to provide prognostic information for single ventricle (SV) patients makes CMR the ideal assessment tool for this patient cohort. Nevertheless, many of the techniques have not yet been incorporated into day-to-day practice.
View Article and Find Full Text PDFSuppression of inflammatory macrophages is a potential strategy to improve rotator cuff healing and has shown promise in preclinical models.
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HSS Sports Medicine Institute, Hospital for Special Surgery; Orthopaedic Soft Tissue Research Program, Hospital for Special Surgery Research Institute. Electronic address:
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View Article and Find Full Text PDFFanlian Huazhuo formula: A promising therapeutic approach for metabolic associated steatotic liver disease.
World J Gastroenterol
January 2025
Department of Biochemistry, School of Medicine, College of Medicine, China Medical University, Taichung 404328, Taiwan.
This article reviews the study, "Fanlian huazhuo formula alleviates high-fat-diet-induced nonalcoholic fatty liver disease by modulating autophagy and lipid synthesis signaling pathway" published in the . The study explores the therapeutic potential of Fanlian Huazhuo formula (FLHZF) in treating metabolic-associated steatotic liver disease (MASLD), demonstrating that FLHZF reduces lipid accumulation, oxidative stress, and liver injury in MASLD models by modulating key signaling pathways involved in lipid metabolism and autophagy. This editorial emphasizes the potential of FLHZF as a treatment for MASLD and calls for further research to verify its clinical efficacy.
View Article and Find Full Text PDFHighly diverse endophytic fungi from Serra do Amolar-Pantanal (Brazil) producing bioactive secondary metabolites against phytopathogens.
Front Microbiol
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Postgraduate Program in Microbiology, Department of Pathology, Federal University of Paraná (UFPR), Centro Politécnico, Curitiba, Paraná, Brazil.
Introduction: The exploration of new bioactive compounds for agricultural applications is critical for sustainable development. Endophytic fungi, particularly those from underexplored biomes in Brazil, represent a promising source of natural compounds. This study focused on isolation and bioprospecting endophytic fungi from the medicinal plant (Pohl), grown in Serra do Amolar (Brazilian Pantanal Biome), with an additional emphasis on conserving microbial biodiversity.
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