AI Article Synopsis

  • Ventricular septal defects are a serious complication that can occur after a heart attack, and if untreated, they have a near 100% mortality rate.
  • Even surgical or other treatment options carry a high risk of mortality, and there are currently no randomized controlled trials to guide optimal treatment approaches.
  • This review aims to detail the diagnosis, effects on blood flow, and treatment options for these defects post-heart attack, highlighting existing research gaps and key questions that need addressing.

Article Abstract

Ventricular septal defects are a rare complication after acute myocardial infarction with a mortality close to 100% if left untreated. However, even surgical or interventional closure is associated with a very high mortality and currently no randomized controlled trials are available addressing the optimal treatment strategy of this disease. This state-of-the-art review and clinical consensus statement will outline the diagnosis, hemodynamic consequences and treatment strategies of ventricular septal defects complicating acute myocardial infarction with a focus on current available evidence and a focus on major research questions to fill the gap in evidence.

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Source
http://dx.doi.org/10.1093/eurheartj/ehae363DOI Listing

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