AI Article Synopsis

  • Cellular movement is crucial for key biological processes, influencing both single-cell activities like division and the collective behavior of cells in tissues for proper development.
  • This movement also plays a significant role in diseases, particularly in cancer metastasis, highlighting its importance in understanding pathology.
  • The text discusses various experimental methods and analytical tools designed to study and quantify the nuances of cell migration, covering both traditional and modern computational techniques.

Article Abstract

Cellular movement is essential for many vital biological functions where it plays a pivotal role both at the single cell level, such as during division or differentiation, and at the macroscopic level within tissues, where coordinated migration is crucial for proper morphogenesis. It also has an impact on various pathological processes, one for all, cancer spreading. Cell migration is a complex phenomenon and diverse experimental methods have been developed aimed at dissecting and analysing its distinct facets independently. In parallel, corresponding analytical procedures and tools have been devised to gain deep insight and interpret experimental results. Here we review established experimental techniques designed to investigate specific aspects of cell migration and present a broad collection of historical as well as cutting-edge computational tools used in quantitative analysis of cell motion.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11180820PMC
http://dx.doi.org/10.3389/fcell.2024.1385991DOI Listing

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